前交通动脉瘤患者认知功能研究

Study of cognitive impairments in patients with aneurysm of the anterior communicating artery

目的研究前交通动脉瘤患者认知功能变化。方法使用简易智能量表评估67例前交通动脉瘤手术治疗患者入院时、出院时和出院后3个月的认知功能。结果 67例前交通动脉瘤患者,在入院时出现认知功能损伤为28例(41.8%),出院时42例(62.7%),出院后3个月24例(36%),患者认知功能损害率出院时高于入院时和出院后3个月时。介入栓塞组和开颅夹闭组患者入院时认知功能损害率分别是33.3%和47.5%,出院时分别为29.6%和85%,出院后3个月时分别为14.8%和50%。结论通过对不同时间段、不同治疗方式的认知功能损害率比较,在前交通动脉瘤治疗过程中选择合适的手术方式及适时早期进行有效的康复治疗措施减少前交通动脉瘤认知功能损害。

Objective The changes of cognitive function of the patients with aneurysm of the anterior communicating artery are studied. MethodsMinimental state examination （MMSE） was used to evaluate the cognitive function of 67 patients with aneurysm of the anterior communicating artery on admission and at discharge from hospital, and at 3 months after discharge from hospital.ResultsThe incidence of cognitive impairment in the patients on admission, at discharge from hospital and at 3 months after discharge from hospital were 41.8%, 62.7% and 36%, respectively. The incidence of cognitive impairment at discharge from hospital was higher than that on admission and 3 months after discharge from hospital. The incidence of cognitive impairment in patients who were treated by interventional embolization and clipping of the aneurysms were 33.3% and 47.5% on admission, 29.6% and 85% at discharge from hospital, and 14.8% and 50% at 3 months after discharge from hospital, respectively.ConclusionAppropriate treatment and timely rehabilitation can reduce the cognitive impairments of the patients with aneurysm of the anterior communicating artery.