祛痹汤内服外洗治疗风湿热痹40例

Forty Cases of Qu Bi Decoction for Oral Administration and External Application in Wind-damp-heat Arthralgia

目的:观察祛痹汤内服、外洗治疗风湿热痹的临床疗效。方法:将80例患者随机分为观察组、对照组各40例。观察组治以祛痹汤,1剂/d,前两煎早晚分服,第3煎熏洗患肢。对照组服用芬必得(布洛芬缓释胶囊)0.3 g/次,2次/d。2组均连续治疗1个月,观察临床疗效及血沉(ESR)、C反应蛋白(CRP)水平。结果:观察组痊愈率为42.5%,总有效率为95.0%;对照组痊愈率为35.0%,总有效率为85.0%,2组比较差异有统计学意义(P<0.05)。ESR、CRP治疗后2组比较,差异有统计学意义(P<0.05)。结论:祛痹汤内服外洗疗法对风湿热痹临床疗效显著,且可降低ESR、CRP。

Objective： To observe the clinical effect of Qu Bi decoction for oral administration and external application in wind-damp-heat arthralgia. Methods： Eighty patients were divided into observation group and control group randomly at forty cases respectively. The observation group was treated with Qu Bi decoction for once daily. The first two tisanes should be taken morning and night respectively while the third tisane should be used for fumigating and washing the affected extremities. The control group was treated with Finpeter Bloven sustained release capsules for 0.3g at a time and twice a day. Both two groups were treated continuously for one month. Clinical effects, erythrocyte sedimentation rates （ESR） and C reactive protein （CRP） levels of the two groups were observed. Results： The cure rate of the observation group was 42.5% while the total effective rate was 95.0%; The cure rate of the control group was 35.0% while the total effective rate was 85.0%. There were statistically significant differences between the two groups in clinical efficacy （P〈0.05）. The difference was statistically significant for the two groups after the ESR and CRP therapies （P 〈0.05）. Conclusion： There is a remarkably clinical effect of Qu Bi decoction for oral administration and external application in wind-damp-heat arthralgia and the levels of ESR and CRP can be reduced as well.