全肠外营养药物使用不合理处方173例分析

Analysis of non-rational prescriptions of 173 cases of total parenteral nutrition

目的 分析全肠外营养（total parenteral nutrition,TPN）药物的不合理使用,为TPN药物的规范化配置提供依据。方法 随机选取本院各科室2015年6~12月TPN处方8722张,统计分析各处方的组成成分。结果 8722张TPN处方中不合理用药处方173张（1.98%）,存在糖脂比不合理（23.12%）、热氮比不合理（24.28%）、电解质用量不合理（32.95%）及丙氨酰-谷氨酰胺用量不合理（19.65%）等问题。结论 为提高临床营养治疗的安全性和有效性,需建立个体化TPN处方审核系统,以进一步规范TPN处方配置。

Objective To analyze the non-rational use of total parenteral nutrition（TPN） drugs in order to provide reference for clinical rational design of TPN drugs. Method 8722 TPN prescription in our hospital from June 2015 to December 2015 were selected, and the composition of the electronic prescription were analyzed. Result 173（1.98%） were non-rational prescriptions in 8722 TPN prescription. The problems were unreasonable ratio of glucose and lipid（23.12%）, unreasonable ratio of heat and nitrogen（24.28%）, irrational electrolyte dosage（32.95%） and the alanyl-glutamine（19.65%）, etc. Conclusion To improve the safety and effectiveness of clinical nutrition therapy, we must establish the prescription audit system to ensure the rationality of TPN prescriptions.