山东省淄博市城区中老年人群骨密度变化及骨质疏松发生率调查

Bone mineral density and osteoporosis incidence in middle-aged and older people in Zibo,Shandong Province

目的总结山东省淄博市城区中老年人群骨密度检测结果,调查骨质疏松症发病情况。方法在2013年5月至2014年6月期间,对淄博市城区的中老年人按年龄组随机抽样的方式选取部分人群进行骨密度检测及骨质疏松症发病情况的调查。用日本ALOKA AOS-100NW超声骨密度仪进行检测,以SOS和T值共同作为骨质疏松症评价指标,并按10岁1年龄段分组进行不同人群结果的比较,计算总体均值;然后统计T值≤-1SD同时>-2.5SD者及≤-2.5SD者人数,计算其占总受检人群的比重,将SOS及T值按男性和女性分别计算均值并予以比较,再将总受检人群按年龄分组分别统计均值并比较和绘图。结果参加骨密度检测的人群共计605人,年龄最小者40岁,最大者92岁,平均年龄57.3±14.3岁。总平均SOS值为:1547.92±217.97m/s;其中男性SOS值为:1576.19±370.42 m/s;女性SOS值为:1532.77±25.87 m/s;男女之间有显著差异(P=0.034)。总平均T值为:-0.24334±4.278SD;其中男性T值为:0.54926±7.121859SD;女性T值为:-0.64765±1.169555SD;均属正常范围,男女之间无显著性差异(P=0.206)。-2.5SD≤T值<-1SD者160人,占总检测人数的26.45%,平均T值为-1.57875±0.402595SD;T值≤-2.5SD者25人,占总检测人数的4.13%,平均T值为-2.84240±0.347662SD;T值<-1SD者总计185人,占总检测人数的30.58%,平均T值为-1.74591±0.586059SD。结论女性平均骨量明显低于男性。男性骨量随年龄增加虽呈下降趋势,但各年龄组差异不大,没有统计学意义;女性伴随年龄增加,骨量明显下降,各年龄组之间差异明显。

Obje ctive To summarize bone mineral density test results of middle-aged and older people in Zibo,Shandong Province,and to investigate the incidence of osteoporosis in this population. Me thods Between 18 May 2013 to 29 June 2014,middle-aged and older people living in Zibo,Shandong Province were randomly sampled according to age groups for bone mineral density measurement and investigation of osteoporosis incidence. Using ALOKA AOS- 100 NW ultrasound bone mineral densitometer（ made in Japan）,SOS and T-score were obtained and used for osteoporosis evaluation. Participants were grouped by age at steps of 10 years,and the mean of each group was calculated and compared in men and women. Graphs were also produced.The percentages of participants with T-score ≤- 1SD and 〉- 2. 5SD persons and ≤- 2. 5SD were calculated. Re sults In total605 people participated in the study,with an age range of 40- 90 years（ mean 57. 29 ± 14. 25 years）. The mean value of SOS was total sample 1547. 92 ± 217. 97 m / sec; male 1576. 19 ± 370. 42 m / sec; female 1532. 77 ± 25. 87 m / sec; there was significant difference（ P = 0. 034） between men and women. The mean of T-score was- 0. 24334 ± 4. 278 SD for total sample; male0. 54926 ± 7. 121859 SD; female- 0. 64765 ± 1. 169555 SD; there were no significant differences（ P = 0. 206） between normal range,men and women. There were 160 participants with T-score between- 1SD and- 2. 5SD,representing 26. 45% of the study population,and the average value of T-score was- 1. 57875 ± 0. 402595 SD. There were 25 participants（ 4. 13%） with T-score ≤2. 5SD,and the average value of T-score was- 2. 84240 ± 0. 347662 SD. There were 185 people（ 30. 58%） who had T-score ≤- 1SD,and the average value of T-score was- 1. 74591 ± 0. 586059 SD. Conclusion Women’s average bone mass was significantly lower than that of men. Bone mass in men although declining with increased age,the differences between age groups were not statistically significant. In women there was a significant decrease in bone mass with increase in age.