野生果树抗肿瘤研究进展

Research Progress of Anti-tumor Effects of Wild Fruit Trees

中国野生果树资源丰富,从野生果树中筛选对恶性肿瘤有抑制作用的药用资源受到学者们的关注,如银杏、白木通、栀子、余甘子、柘、胡颓子等一些野生果树的提取物,在体内或体外的抗肿瘤实验中有杀死某些肿瘤细胞的作用,并显示其抗肿瘤机制可能与提高机体的免疫作用有关。通过总结在抗肿瘤研究方面取得进展的上述野生果树种类,并对其药用成分,对肿瘤细胞的抑制作用及抗癌机制等相关研究进展进行综述,为野生果树药用价值的研究开发及合理应用提供参考,并对药用型野生果树在肿瘤防治方面的应用前景进行了展望。

China has abundant wild fruit tree resources. Scholars have paid much attention to medicalresources in wild fruit trees which have inhibitory effects on cancer. In vivo or vitro anti-tumor experimentsshowed that extracts of some wild fruit trees, such as Ginkgo biloba, Akebia trifoliata, Gardenia jasminoides,Phyllanthus emblica, Maclura tricuspidata, Elaeagnus, had great effects on killing tumor cells. The results ofthese experiments also showed that anti-tumor mechanism might play an important role in improving bodyimmune functions. We summarized the research progress of medical ingredients, inhibiting effects on tumorcells and anti-tumor mechanism of the above wild fruit tree species. The research could provide a reference fordevelopment and reasonable application of wild fruit trees＇ medical value. Finally, we made an outlook onprevention and treatment of tumor by using medicinal-type wild fruit trees in the future.