摘要
基质金属蛋白酶(MMPs)是降解细胞外基质的重要酶类之一,在根尖周病的发生发展中起重要作用,已证实在根尖周病变的组织中主要存在MMP-1、-2、-8、-9、-13。本文就MMPs在根尖周病中的作用作一综述。
Matrix metaUoproteinases （MMPs） are a group of important enzymes degrading extracellular ma- trix. It has been found that MMPs play important roles in the development of periapical lesions. The major MMPs in periapical tissues of periapical periodontitis are MMP - 1, - 2, - 8, - 9 and MMP - 13. This paper reviews the roles of MMPs, particularly MMP - 1, -2, -8, -9 and MMP - 13, in the pathogenesis of periapical lesions.
作者
范挽亭
张铮
张国志
黄世光
FAN Wan-ting ZHANG Zheng ZHANG Guo-zhi HUANG Shi-guang(Oral Medical Center, Shenzhen People＇ s Hospital, Second Clinical Medical College of Jinan University, Shenzhen 518020, China)
出处
《牙体牙髓牙周病学杂志》
CAS
2016年第10期629-633,共5页
Chinese Journal of Conservative Dentistry
基金
广东省社会发展领域科技计划项资助项目(2013B021800043
2014A020212212)
