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2016年拉斯克奖

The 2016 Lasker Awards
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摘要 北京时间2016年9月13日,拉斯克奖获奖者名单公布。基础医学奖颁发给William G.Kaelin,Jr.、Peter J.Ratcliffe以及Gregg L.Semenza,以表彰他们发现了人体和大多数动物细胞感知和适应氧气变化机制。临床医学研究奖颁发给Ralf F.W.Bartenschlager、Charles M.Rice以及Michael J.Sofia,以表彰他们对丙型肝炎的"复制子"系统的研究及药物的研发。特殊贡献奖颁发给Bruce M.Alberts,以表彰他在DNA复制和蛋白质生化研究方面的发现,在国家和国际科研机构中为改善人类生活而展现出的富有远见的领导力,以及在改进科学和教育方面所做出的杰出贡献。 In September 13,2016,the list of winners of the year's Lasker Awards were released. The 2016 Albert Lasker Basic Medical Research Award honors William G. Kaelin,Jr.,Peter J. Ratcliffe and Gregg L. Semenza,for their discovery of the pathway by which cells from human and most animals sense and adapt to changes in oxygen availability,a process that is essential for survival. The2016 Albert Lasker Clinical Medical Research Award honors Ralf F. W. Bartenschlager,Charles M. Rice and Michael J. Sofiafor,who developed a system to study the replication of the virus that causes hepatitis C and used this system to revolutionize the treatment of this chronic,often lethal disease. The 2016 Lasker Award for Special Achievement in Medical Science honors Bruce M. Alberts for fundamental discoveries in DNA replication and protein biochemistry; for visionary leadership in directing national and international scientific organizations to better people's lives; and for passionate dedication to improving education in science and mathematics.
出处 《首都医科大学学报》 CAS 北大核心 2016年第5期703-710,共8页 Journal of Capital Medical University
关键词 拉斯克奖 HIF-1 丙型肝炎病毒 DNA复制 Lasker Awards HIF-1 hepatitis C virus(HCV) DNA replication
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  • 1朱安远,郭华珍.诺贝尔奖的风向标——美国拉斯克奖概览[J].中国市场,2016(5):183-194. 被引量:9
  • 2Evelyn Strauss. THE 2016 LASKER AWARDS. (2016 - 09 - 13 ) [ 2016 - 09 - 27 ]. http://www. laskerfoundation, org/.
  • 3Semenza G L, Rue E A, Iyer N V, et al. Assignment of the hypoxia-inducible factor 1 alpha gene to a region of con- served synteny on mouse chromosome 12 and human chro- mosome 14q[J]. Genomics, 1996, 34(3) : 437 -439.
  • 4Tan C C, Eckardt K U, Firth J D, et al. Feedback modula- tion of renal and hepatic erythropoietin mRNA in response to graded anemia and hypoxia[ J]. Am J Physiol, 1992, 263 (3 Pt 2) : F474 - F481.
  • 5Tan C C, Eekardt K U, Rateliffe P J. Organ distribution of erythropoietin messenger RNA in normal and uremic rats [J]. Kidneylnt, 1991,40(1): 69-76.
  • 6Rateliffe P J, Jones R W, Phillips R E, et. al. Oxygen-de- pendent modulation of erythropoietin mRNA levels in isola- ted rat kidneys studied by RNase proteetion[ J ]. J Exp Med, 1990, 172(2): 657-660.
  • 7Minamishima Y A, Kaelin W J. Reactivation of hepatic EPO synthesis in mice after PHD loss[J]. Science, 2010, 329 (5990) : 407.
  • 8Sellers W R, Novitch B G, Miyake S, et al. Stable binding to E2F is not required for the retinobiastoma protein to acti- vate transcription, promote differentiation, and suppress tumor cell growth[J]. Genes Dev, 1998, 12(1): 95 - 106.
  • 9Epstein A C, Gleadle J M, McNeill L A, et al. C. elegans EGL-9 and mammalian homologs define a family of dioxyge- nases that regulate HIF by prolyl hydroxylation [ J ]. Cell, 2001, 107(1) : 43-54.
  • 10Takeuchi K, Boonmar S, Kubo Y, et al. Hepatitis C viral cDNA clones isolated from a healthy carrier donor implica- ted in post-transfusion non-A, non-B hepatitis [ J ]. Gene, 1990, 91(2): 287-291.

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