新生儿非甲状腺疾病综合征的研究进展

The Research Progress of Neonatal Non-Thyroidal Illness Syndrome

非甲状腺疾病综合征(NTIS)在绝大部分急、慢性疾病中均表现为甲状腺激素水平的异常。近年来,NTIS在新生儿中并不罕见。甲状腺功能异常改变的类型呈多样性,致病原因可能包括窒息缺氧、感染性疾病、胎龄、母亲相关因素及能量摄入不足等。其致病机制较为复杂,目前尚不明确,可能为多种因素共同作用的结果。而关于NTIS是否需要治疗仍未有定论。

The non-thymidal illness syndrome（NTIS） ,reflects alterations in thyroid hormone levels that occur in almost every form of acute or chronic illness. In recent years, it is not rare in the newborns. The feature of thyroid dysfunction is various. The etiologic factors may include asphyxia, infection, gestational age, maternal factors and diseases,inadequate caloric intake and so on. The pathogeneses behind NTIS are complex which may be associated with multiple factors. They are yet not fully understood so far. The question of whether patients with the NTIS need treatment remains inconclusive.