腹腔镜对良性卵巢囊肿患者的治疗效果及对卵巢功能的影响

Treatment Effect of Laparoscopy for Benign Ovarian Cysts and Its Effect on Ovarian Function

目的分析腹腔镜对良性卵巢囊肿患者的治疗效果及对卵巢功能的影响。方法选取2014年1月至2015年1月自贡市妇幼保健院收治的120例良性卵巢囊肿患者为研究对象,按照抽签法分为观察组与对照组,每组60例。观察组患者予以腹腔镜手术治疗,对照组采用传统的开腹手术治疗。观察比较两组患者的手术情况(手术时间、术中出血量、抗生素使用时间、肛门通气时间、住院时间),治疗前后月经与性激素水平(促卵泡激素、黄体生成素、雌二醇)变化的情况,临床疗效,满意度及并发症发生情况。结果观察组患者手术时间、术中出血量、抗生素使用时间、肛门通气时间及住院时间均少于对照组[(63±9)min比(87±8)min,(76±8)m L比(127±9)m L,(1.45±0.27)d比(2.58±0.31)d,(1.14±0.23)d比(2.24±0.26)d,(4.4±0.6)d比(7.0±0.6)d],差异有统计学意义(P<0.01)。治疗后,观察组促卵泡激素、黄体生成素水平高于对照组[(15.8±2.0)U/L比(8.7±1.3)U/L,(16.0±2.2)U/L比(8.7±1.2)U/L],雌二醇水平低于对照组[(29.0±3.7)ng/L比(47.7±6.9)ng/L],差异有统计学意义(P<0.01)。治疗后,观察组月经异常合计的比例均低于对照组[21.7%(13/60)比68.3%(41/60)],差异有统计学意义(P<0.05)。观察组总有效率、总满意度高于对照组[96.7%(58/60)比73.3%(44/60),98.3%(59/60)比66.3%(41/60)],并发症发生率低于对照组[0%比8.3%(5/60)],差异有统计学意义(P<0.05)。结论腹腔镜手术治疗良性的卵巢囊肿效果良好,对卵巢的功能影响较小,术中出血量较少,住院时间短,术后恢复快,值得临床广泛推广。

Objective To analyze the effect of laparoseopy for benign ovarian eysts, and the impact on ovarian function. Methods Total of 120 cases of benign ovarian cysts admitted to Zigong Maternal and Child Health Hospital from Jan. 2014 to Jan. 2015 were included in the study and divided into an observation group and a control group according to the draw method ,60 cases each. The observation group reeeived laparoscopic surgery, and the control group received traditional open surgery. The surgery conditions （ surgery time,intranperative blood loss, antibiotic usage time, anal ventilation time, hospitalization time） , menstruation and sex hormone levels of follicle-stimulating hormone （ FSH ）, luteotropic hormone （ LH ）, estradiol （E2 ） changes, treatment effectiveness, satisfaction and complications of the two groups were compared. Results Operative time, blood loss, antibiotics usage time, anal ventilation time and hospital stay of the observation group were less than those of the control group [ （63±9） min vs （ 87 ±8 ） min, （76 ± 8 ） mL vs （127±9） mL,（1.45±0.27） d,vs （2.58 ±0.31） d,（1.14±0.23） dvs （2.24±0.26） d,（4.4±0.6） dvs （7.0 ± 0. 6） d ] ,the differences were statistically significant （P 〈 0.01 ）. After treatment, FSH, LH of the observation group were higher than those of the control group [ （ 15.8 ± 2.0 ） U/L vs （ 8.7 ±1.3 ） U/L, （ 16. 0 ± 2.2） U/L vs （8.7 ± 1.2） U/L] , E2 was lower than the control group [ （29.0 ± 3.7 ） ng/L vs （47.7± 6.9 ） ng/L ], the difference was statisticdlly significant （P 〈 0.01 ）. After treatment, total percentage of menstrual abnormalities of the observation group was lower than the control group [ 21.7% （ 13/60 ） vs 68.3 % （41/60 ） ], the difference was statistically significant （P 〈 0. 05 ）. The total effective and overall satisfaction of the observation group were higher than those of the control group[ 96.7% （ 58/60 ） vs 73.3% （44/60） ,98.3% （59/60） vs 66. 3%（41/60） ] ,complication rate was lower than the control group[0% vs 8.3 % （5/60） ], the difference was statistically significant （P 〈 0. 05 ）. Conclusion Laparoscopic treatment of benign ovarian cysts has good effect,with little influence on ovarian function,less intraoperative blood loss, shorter hospital stays and faster recovery after surgery, thus is worthy of the clinical application.