亚临床甲状腺功能减退与代谢综合征患者胰岛素抵抗及血清CRP的相关性被引量：2

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摘要目的探讨代谢综合征(MS)患者血清促甲状腺激素(TSH)水平与胰岛素抵抗及血清高敏C-反应蛋白(hs-CRP)的相关性。方法将92例MS患者根据血清TSH水平分为亚临床甲状腺功能减退组(SCH组)及正常甲状腺功能组(EUT组),测定甲状腺功能、空腹血糖(FPG)、空腹胰岛素(FINS)、hs-CRP、血脂及糖化血红蛋白(Hb A1c)水平,利用稳态模型计算胰岛素抵抗指数(HOMA-IR)。结果 SCH组血清TSH、FINS较EUT组明显升高(P<0.05);HOMA-IR较EUT组升高(P<0.05);TSH与FINS、HOMA-IR呈正相关(r=0.484、0.473,P<0.05);两组间hs-CRP无统计学差异(P>0.05)。结论血清TSH水平升高是MS患者空腹高胰岛素血症及胰岛素抵抗的危险因素。

作者卢薇许小红袁娟

机构地区贵阳市第一人民医院内分泌科

出处《临床医学研究与实践》 2016年第22期10-11,共2页 Clinical Research and Practice

基金基金项目:贵阳市卫生局[2014]筑卫科技合同字第1号

关键词代谢综合征亚临床甲状腺功能减退胰岛素抵抗高敏C反应蛋白

分类号 R581 [医药卫生—内分泌]

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