硫酸镁联合硝苯地平治疗妊娠期高血压综合征的临床价值探究

Clinical value of magnesium sulfate combined with nifedipine on pregnancyinduced hypertension

目的探究硫酸镁与硝苯地平在妊娠期高血压综合征治疗中的疗效。方法选取我院收治的妊娠期高血压综合征患者160例为研究对象,按照入院治疗的先后顺序将其分为对照组和观察组,各80例。对照组患者给予硫酸镁治疗,观察组患则给予硫酸镁与硝苯地平联合治疗,比较两组患者的临床疗效。结果观察组患者治疗总有效率高于对照组、血压控制情况优于对照组、不良分娩结局发生率低于对照组,差异均有统计学意义(P<0.05)。结论硫酸镁与硝苯地平在妊娠期高血压综合征治疗中能够增强降压效果,改善患者分娩结局,值得推广。

Objective To investigate the clinical effect of magnesium sulfate combined with nifedipine on pregnancyinduced hypertension. Methods One hundred and sixty cases of patients with pregnancy-induced hypertension admitted in our hospital were selected and divided into control group and observation group according to the date of admission, with 80 cases in each group. The patients in the control group were treated with magnesium sulfate, while patients in the observation group were given sulfate combined with nifedipine. The clinical effects of the two groups were compared. Results The effective rate of observation group was higher than that of the control group, the blood pressure control of the observation group was better than that of the control group, and the incidence of adverse birth outcomes rate was lower than that of the control group; the differences all had statistical significance （P〈0.05）. Conclusion Magnesium sulfate combined with nifedipine on pregnancy-induced hypertension can increase antihypertensive efficacy and improve birth outcomes, which is worthy of popularizing.