刃针联合隔姜灸治疗膝骨关节炎疗效观察

Clinical effects of knife needle combined with ginger moxibustion on the treatment of knee osteoarthritis

目的观察刃针联合隔姜灸治疗膝骨关节炎的临床疗效。方法将100例膝骨关节炎患者随机分为2组。对照组50例予硫酸氨基葡萄糖胶囊、塞来昔布胶囊治疗,治疗组50例予刃针联合隔姜灸治疗。2组均治疗6周后统计临床疗效,并观察2组治疗前后骨性关节炎指数可视化量表(WOMAC)、视觉模拟评分(VAS)及血液流变学指标变化。结果治疗组总有效率92.00%,对照组总有效率64.00%,2组比较差异有统计学意义(P<0.05),治疗组疗效优于对照组。治疗组治疗前后WOMAC评分差值为(32.20±6.24)分,对照组治疗前后WOMAC评分差值为(26.14±4.98)分,2组比较差异有统计学意义(P<0.05)。治疗组WOMAC评分与时间呈线性递减关系(Y=-5.35X+63.75,R2=0.99),而对照组不存在线性关系(Y=-3.11X+57.21,R2=0.68),提示治疗组疗效较对照组稳定。2组治疗后VAS评分均降低(P<0.05),治疗组治疗后VAS评分明显低于对照组治疗后(P<0.05);2组治疗前后VAS差值比较,治疗组改善程度明显优于对照组(P<0.05)。2组血液流变学检查治疗前均存在1项及以上异常,其中治疗组3项以上异常者39例,对照组44例;治疗后,治疗组恢复正常率为87.17%(34/39),对照组恢复正常率为81.82%(36/44),2组比较差异无统计学意义(P>0.05)。治疗组治疗后红细胞沉降率(ESR)(6.98±2.07)mm/1h,对照组治疗后ESR(9.87±2.95)mm/1h,2组比较差异有统计学意义(P<0.05)。结论刃针联合隔姜灸治疗膝骨关节炎疗效确切,并能改善WOMAC、VAS评分。

Objective To observe the clinical effects of knife needle combined with ginger moxibustion on the treatment of knee osteoarthritis. Methods 100 patients with knee osteoarthritis were randomly divided into two groups. 50 cases in control group were treated by glucosamine sulfate capsules and celecoxib capsule,and 50 cases in treatment group were treated by knife needle combined with ginger moxibustion. The curative effect was evaluated after 6 weeks treatment in two groups. The Western Ontario and Mc Master Universities osteoarthritis index（ WOMAC）,Visual Analogue Score（ VAS） and the parameters of hemorheology before and after treatment were observed. Results The total effective rate in treatment group（ 92. 00%） was superior to that in control group（ 64. 00%,P〈0. 05）.The difference between before and after treatment of WOMAC in treatment and control group were（ 32. 20 ± 6. 24）and（ 26. 14 ± 4. 98） respectively,with statistical differences（ P〈0. 05）. There were linear decrease relationship between WOMAC and time in treatment group（ Y =- 5. 35 X ＋ 63. 75,R^2= 0. 99）,and the control group had nonlinear correlation（ Y =- 3. 11 X ＋ 57. 21,R2= 0. 68）,which showed that the curative effect in treatment group was more stable than that in control group. The VAS after treatment was decreased in two groups（ P〈0. 05）,and the scores of VAS after treatment in treatment group were obvious lower than control group（ P〈0. 05）. Compared the difference between before and after treatment of VAS,the improvment in treatment was better than that in control group（ P〈0. 05）. There were one item and one item above of abnormal blood hemorheology before treatment in two groups,and over 3 items of abnormal blood hemorheology in treatment and control group were 39 and 44 cases respectively. After treatment,the recovery rate in treatment and control groups were 87. 17%（ 34 /39） and 81. 82%（ 36 /44） respectively,with no statistical differences（ P〈0. 05）. The ESR after treatment in treatment and control groups were（ 6. 98 ± 2. 07） mm /1h and（ 9. 87 ± 2. 95）mm /1h respectively,with statistical differences（ P〉0. 05）. Conclusion Knife needle combined with ginger moxibustion has exact effects on the treatment of knee osteoarthritis,can improve the scores of WOMAC and VAS.