达英-35联合二甲双胍治疗多囊卵巢综合征后促排卵效果分析

Analysis of Ovulation Induction Effect of Treating PCOS with Diane-35 Combined Metformin

目的:探讨达英-35联合二甲双胍对多囊卵巢综合征以及促排卵效果的影响。方法 :67例多囊卵巢综合征患者随机分为对照组和观察组,对照组33例单独应用达英-35治疗,观察组34例给予达英-35联合二甲双胍治疗。结果:治疗后体重和体重指数均有下降,观察组下降更为明显,组间比较具有统计学意义(P<0.05)。治疗后T、LH激素水平较治疗前均有明显降低,组内比较差异具有统计学意义(P<0.05)。FSH、PRL以及E2治疗前后以及治疗后组间比较均无统计学意义(P>0.05),观察组妊娠率显著高于对照组。结论:达英-35联合二甲双胍治疗多卵巢综合征具有显著疗效,能够有效改善患者内分泌失调症状,提高促排卵效果,提高患者妊娠率。

Objective： To explore ovulation induction effect of treating PCOS with Diane-35 combined metformin. Methods： 67 cases of patients with p01ycystic ovary syndrome were randomly divided into control group and observation group, control group 33 cases treated with Diane-35, observation group of 34 cases treated with Diane-35 combined metformin. Results： After treatment there is a decrease in the weight and body mass index, the observation group decreased more significantly than the control group, with statistical significance （P〈0.05）. T, LH hormone levels after treatment decreased significantly than that before treat- ment （P〈0.05）. FSH, PRL, Ez before and after the treatment had no statistical significance （P〈0.05）. The pregnancy rate of observation group is significantly higher than that of the control group. Conclusion：Diane-35 combined metformin has significant curative effect in treating PCOS.