摘要
目的了解北京市急性HBV经血和性接触传播的危险因素。方法选择2013年1月至2014年12月国家法定传染病信息报告系统中的急性乙型肝炎患者301例,采用1:2配对方法选取与患者性别、年龄和居住街(乡)相同的健康者602名作为健康对照。对所有病例和对照进行感染危险因素问卷调查。组间比较采用X2检验,Logistic回归分析急性HBV经血和性接触传播的危险因素。结果单因素分析发现,目前北京市急性HBV经血和性接触传播的主要危险因素为半年以上医疗机构注射药物史(X2=5.45,p=0.03)、手术史(X2=6.94,P=0.01)、龈上洁治术(X2=4.21,P=0.05)、捐献成分血(X2=4.43,P=0.04)、家庭成员密切接触史(X2=8.19,P=0.01)、修足(X2=4.41,P=0.04)、刮痧(X2=6.94,P=0.01)、拔罐(X2=8.94,P=0.00)。多因素条件Logistic分析将单因素分析有意义的危险因素带入方程中,结果发现半年以上医疗机构注射药物史(OR=3.44,95%CI:1.31~9.01)、手术史(OR=4.03,95%CI:1.44~11.30)、家庭成员密切接触史(OR=3.17,95%CI:1.32~7.65)和拔罐(OR=1.87,95%CI:1.03~3.40)是目前北京市急性HBV经血和性接触传播的危险因素。多因素条件Logistic分析将所有危险因素变量带入方程中,结果发现手术史(OR=1.45,95%CI:1.45~26.84)和文眉、文眼线、文身等创伤性医学美容史(OR=6.83,95%CI:1.06~44.16)是目前北京市急性HBV经血和性接触传播的危险因素。结论北京市急性HBV经血和性接触传播危险因素为半年以上医疗机构注射药物史,手术史、家庭成员密切接触史、拔罐和创伤性医学美容史。
Objective To investigate the risk factors of acute hepatitis B virus through blood and sexual contact transmission in Beijing. Methods A population-based 1:2 matched case-control study was used in our survey. Three hundred and one acute hepatitis B cases living in Beijing more than one year reported in National Notifiable Disease Reporting System from January 2013 to December 2014 were recruited as cases. Six hundred and two sex-, age- and resident-matched individuals were selected as controls, All cases and controls were interviewed by questionnaires. Categorical variables were compared using chi-square test between groups. Risk factors for acute hepatitis B virus through blood and sexual contact transmission were calculated by Logistic regression model. Results Univariate factor analysis showed that history of drug injection in hospital more than half a year (X2 = 5.45, P= 0.03), surgery (X2 = 6.94, P= 0.01 ), supragingival scaling (X2= 4.21, P = 0.05), component blood donation (X2= P=0. 04), close household contact (X2 =8.19, P=0. 01) ,pedicure (X2=4.41, P=0. 04), scraping 4. 43, (X2 =6.94, P=0.01) and cupping (X2= 8. 94, P= 0.00) were the risk factors for acute hepatitis B virus through blood and sexual contact transmission. Multivariate Logistic analysis enrolled risk factors with significance into equation and showed that history of drug injection in hospital more than half a year (OR= 3.44, 95% CI:1.31-9.01), surgery (OR=4.03, 95% CI: 1.44-11.30), close household contact (OR= 3.17, 95% CI: 1.32- 7.65) and cupping (OR = 1.87, 95% CI: 1.03 - 3.40) were the risk factors for acute hepatitis B virus through blood and sexual contact transmission. Multivariate Logistic analysis enrolled all risk factors into equation and showed that history of surgery (OR= 1.45, 95% CI:1.45- 26.84), traumatic medical cosmetology (OR = 6. 83, 95% CI:1.06- 44. 16) were the risk factors for acute hepatitis B virus through blood and sexual contact transmission. Conclusion History of drug injection in hospital more than half a year, surgery, close household contact, cupping and traumatic medical cosmetology are the risk factors for acute hepatitis B virus through blood and sexual contact transmission in Beijing.
出处
《中华传染病杂志》
CAS
CSCD
北大核心
2016年第9期536-539,共4页
Chinese Journal of Infectious Diseases
关键词
肝炎
乙型
急性
血液
性行为
危险因素
病例对照研究
Hepatitis B
Acute
Blood
Sexual behavior
Risk factors
Case-control studies