麻黄强化泡沫分离甘草酸的工艺研究

Study on Ephedra Intensified Foam Fractionation of Glycyrrhizic Acid

为了提高泡沫分离甘草中甘草酸的分离效果,开发了甘草麻黄配伍泡沫分离工艺,并就麻黄对浸提液泡沫性能的影响进行了研究。结果表明,麻黄强化了甘草酸的提取,但降低了浸提液中甘草苷的浓度,使得浸提液的泡沫性能发生变化而影响泡沫分离甘草酸的分离效果。以甘草酸的富集比和回收率为评价指标,研究了温度、气体体积流量、甘草酸初始浓度和甘草麻黄质量配比对分离效果的影响。结果表明当温度为40℃、气体体积流量为100 m L×min^(-1)、甘草酸初始浓度为0.2 g×L^(-1)和甘草麻黄质量配比为5:3时,获得甘草酸的富集比和回收率分别为8.34和62.5%。与单独泡沫分离甘草中甘草酸相比,甘草酸的富集比提高了121.7%,而回收率并未明显降低。因此,麻黄的引入有效地提高了泡沫分离甘草酸的分离效果。

In order to improve foam fractionation performance of glycyrrhizic acid from Glycyrrhiza, a noveltechnology for foam fractionation using Glycyrrhiza and Ephedra was developed and the effect of Ephedra onfoaming performance of the leaching liquor was studied. The results show that Ephedra enhances extraction ofglycyrrhizic acid. Furthermore, Ephedra decreases the concentration of liquiritin in the leaching liquor and thusaffects its foaming performance. Enrichment ratio and recovery percentage were used as the evaluation indexesand the effects of temperature, volumetric air flow rate, initial concentration of glycyrrhizic acid and mass ratioof Glycyrrhiza and Ephedra on foam fractionation performance were investigated. The results show that theenrichment ratio and the recovery percentage of glycyrrhizic acid are 8.34 and 62.5%, respectively, whenstudied under conditions of temperature 40℃, volumetric air flow rate 100 mL.min-1, initial concentration ofglycyrrhizic acid 0.2 g·L-1 and mass ratio of Glycyrrhiza and Ephedra 5：3. Compared to the technology of foamfractionation with Glycyrrhiza, the method used increases the enrichment ratio by 121.7% and does notsignificantly reduce the recovery percentage. Therefore, the addition of Ephedra effectively improves the foamfractionation performance of glycyrrhizic acid.