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丙泊酚对水通道蛋白家族影响的相关研究

Researches on the effect of propofol on aquaporins
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摘要 颅内占位性病变、颅脑损伤、脑血管疾病和脑代谢功能障碍等均可引起脑水肿,而水通道蛋白(AQP)是控制脑水肿的重要蛋白。丙泊酚能够通过多种途径影响水通道蛋白,从而控制脑水肿,本文对丙泊酚对AQP的影响进行综述。 Intracranial space-occupying lesion,brain injury,cerebrovascular disease and cerebral metabolic dysfunction can cause cerebral edema,and aquoporins（AQP） is an important protein in controlling the cerebral edema.Propofol can affect AQP through various channels and thus control brain edema.The paper reviews the effect of propofol on aquoporin pathway.
作者 李春雷 宋春雨
机构地区 哈尔滨医科大学附属第二医院麻醉科
出处 《实用药物与临床》 CAS 2016年第10期1303-1306,共4页 Practical Pharmacy and Clinical Remedies
基金 国家自然科学基金青年项目(81301668)
关键词 丙泊酚 水通道蛋白 脑水肿 Propofol Aquaporins Brain edema
分类号 R614 [医药卫生—麻醉学]
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参考文献28

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