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血浆和肽素及N末端脑钠肽前体与射血分数保留的心力衰竭相关性研究 被引量:5

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摘要 目的探索血浆和肽素、N末端脑钠肽前体(NT-proBNP)和射血分数保留的心力衰竭(HFpEF)的相关性。方法检测HFpEF患者(57例)和健康者(30例)血浆和肽素、NT-proBNP水平,同时检测心脏结构和功能指标。结果与健康者相比,HFpEF患者血浆和肽素、NT-proBNP水平显著升高(P<0.05),且随美国纽约心脏病协会(NYHA)分级增加而升高。血浆和肽素水平与NYHA分级、左室舒张末期内径、舒张早期二尖瓣血流峰值与舒张早期二尖瓣环心肌运动速度比值、血肌酐、NT-proBNP正相关(P<0.05)。结论血浆和肽素、NT-proBNP水平HFpEF患者中明显升高,并与患者病情严重程度密切相关。
出处 《检验医学与临床》 CAS 2016年第20期2942-2944,共3页 Laboratory Medicine and Clinic
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