浅析银杏达莫联合依达拉奉治疗急性脑梗死的临床疗效及安全性

Brief analysis of clinical effect and safety by ginkgo-damole and edaravone in the treatment of acute cerebral infarction

目的探讨急性脑梗死患者使用银杏达莫联合依达拉奉治疗的临床效果和安全性。方法 79例急性脑梗死患者,随机分成对照组(38例)和观察组(41例),对照组单纯给予依达拉奉治疗,观察组给予银杏达莫联合依达拉奉治疗。对比两组的临床疗效。结果经过治疗,观察组临床总有效率为95.12%,高于对照组的78.95%(P<0.05)。观察组平均神经功能缺损评分为(13.43±2.03)分,低于对照组的(17.89±3.27)分(P<0.05)。观察组不良反应发生率为7.32%,低于对照组的23.68%(P<0.05)。结论银杏达莫和依达拉奉联合治疗急性脑梗死具有非常好的效果,比单纯依达拉奉治疗效果优秀,值得推广使用。

Objective To investigate clinical effect and safety by ginkgo-damole and edaravone in the treatment of acute cerebral infarction. Methods A total of 79 patients with acute cerebral infarction were randomly divided into control group（38 cases） and observation group（41 cases）. The control group received edaravone alone for treatment, and the observation group received ginkgo-damole and edaravone. Clinical effects were compared between the two groups. Results After treatment, the observation group had higher total clinical effective rate as 95.12% than 78.95% in the control group（P〈0.05）. The observation group had lower mean neurological functional deficit score as（13.43±2.03） points than（17.89±3.27） points in the control group（P〈0.05）. The observation group had lower incidence of adverse reaction as 7.32% than 23.68% in the control group（P〈0.05）. Conclusion Combination of ginkgo-damole and edaravone shows excellent effect in treating acute cerebral infarction. This method is better than single treatment by edaravone, and it is worth promoting and applying.