妊娠合并甲减对妊娠结局及胎儿的影响研究

The Effect of Hypothyroidism on Pregnancy Outcome of Pregnancy and Fetal

目的对妊娠合并甲减对妊娠结局及胎儿的影响研究的分析和探讨。方法选取2014年6月~2015年6月我院收治的90例妊娠合并甲减患者,按照入院顺序分为对照组和试验组,各45例,其中对照组不使用左旋甲状腺素钠治疗,试验组给予左旋甲状腺素钠进行治疗,观察两组的患者并发症发生情况、妊娠结果和胎儿情况。结果试验组患者并发症发生妊娠高血压、胎儿宫内窘迫、妊娠肝内胆汁淤积症低于对照组,差异具有统计学意义（P〈0.05）。试验组患者妊娠结果和胎儿情况优于对照组,差异具有统计学意义（P〈0.05）。结论妊娠合并甲减患者会使最终产生不良的妊娠结局,同时对胎儿的发育造成不良影响。

Objective Analysis and discussion on the research of effect on the outcome of pregnancy and fetal maternal hypothyroidism. Methods From June 2014 to June 2015, 90 cases of pregnant women with hypothyroidism in our hospital were divided into control group and experimental group according to the order of admission,45 cases in each group. The control group did not use of L-thyroxine treatment. The experimental group was given levothyroxine sodium treatment,two groups of patients with complications,pregnancy outcomes and the condition of the fetus. Results In the experimental group,patients with complications（hypertension of pregnancy,fetal distress,glucose metabolism abnormalities and intrahepatic cholestasis of pregnancy）were lower than that of the control group,the difference was statistically significant（P〈 0.05）. Patients in the experimental group＇s pregnancy and fetal outcome were better than that of the control group,the differences was statistical significance（P〈 0.05）. Conclusion Pregnancy complicated with hypothyroidism patients will eventually produce adverse pregnancy outcomes,at the same time,cause adverse effects on fetal development.