摘要
目的探讨中药止咳汤剂对急性气管炎患者血清中白三烯C4（LTC4）和血小板活化因子（PAF）的影响。方法将我院2014年1~12月收治的64例急性气管炎的患者为观察对象,随机分为观察组和对照组,各32例,对照组采用西药治疗,观察组采用中药止咳汤剂治疗,观察比较两组患者的症状积分、LTC4和PAF。结果两组患者治疗后均较治疗前改善,且观察组患者治疗后症状总积分优于对照组,差异具有统计学意义（P〈0.05）;观察组治疗后的PAF和LTC4值较治疗前改善,且差异具有统计学意义（P〈0.01）,与空白对照组相近。对照组患者治疗后的PAF和LTc4值较治疗前改善,但LTC4和PAF比值仍高于空白对照组1倍左右。结论中药止咳汤剂不可以有效的改善急性气管炎的症状,而且可以有效的拮抗气道炎症介质LTC4和PAF。
Objective To study the clinical effect of TCM decoction of cough suppressant in the serum LTC4 and platelet activating factor（PAF）for patients with acute bronchitis. Methods 64 patients with acute bronchitis treated from January 2014 to December 2014 in our hospital were selected,the subjects were randomly divided into two groups,32 cases each group. The control group took the western medicine,the observation group adopted the TCM decoction of cough suppressant. The symptom score,LTC4 and PAF for two group was observed. Results The total symptom scores for observation group were even better than control group（P 0.05）,the value of PAF and LTC4 for observation group was better than before（P 〈0.01）. Its value was close to normal group,the value of PAF and LTC4 for control group was better than before,which was one time higher than normal group. Conclusion The TCM decoction of cough suppressant can effectively improve the clinical symptoms of acute bronchitis as well as the index of LTC4 and PAF.
出处
《中国卫生标准管理》
2016年第19期110-112,共3页
China Health Standard Management
