血清CEA、CA19-9及铁蛋白联合检测在胰腺癌诊断中的价值

Value of Combination Detection of Serum CEA,CA19-9 and Ferritin in Diagnosing Pancreatic Cancer

目的探讨血清癌胚抗原(CEA)、糖类抗原19-9(CA19-9)及铁蛋白联合检测在胰腺癌诊断中的价值。方法选取胰腺癌患者50例(胰腺癌组),慢性胰腺炎患者50例(慢性胰腺炎组)及体检健康者50例(对照组)。结果胰腺癌患者血清CEA、CA19-9及铁蛋白的表达水平均高于慢性胰腺炎组和对照组,差异均有统计学意义(P<0.05);不同TNM分期胰腺癌患者血清CEA、CA19-9及铁蛋白表达水平比较,差异均有统计学意义(P<0.05)。结论血清CEA、CA19-9及铁蛋白联合检测对胰腺癌的诊断有着重要的参考价值。

Objective To explore the value of the combination detection of serum CEA,CA19-9 and ferritin in the diagnosis of pancreatic cancer.Methods50 patients conducted pancreatic cancer（pancreatic caner group）,50 patients with chronic pancreatitis（chronic pancreatitis group）and 50 healthy persons conducted physical examination（control group）in our hospital were recruited for this study.Results The serum CEA,CA19-9 and ferritin expression levels in the pancreatic cancer group were significantly higher than those in the chronic pancreatitis group and the control group,the differences had statistical significance（P 〈0.05）,the serum CEA,CA19-9 and ferritin expression levels had the statistical differences among different stages of TNM classification（P〈 0.05）. Conclusion The combination detection of serum CEA,CA19-9 and ferritin could have important reference value for the diagnosis of pancreatic cancer.