肿瘤细胞原血红素a/b/c检测在健康体检宫颈癌检出中的应用分析

Application of Hematopoietic a/b/c Examination in the Detection of Cervical Cancer in Healthy Physical Examination

目的分析健康体检时进行宫颈渗液肿瘤细胞原血红素a/b/c检测筛查结果,并验证检测方法的有效性。方法某体检中心对19970名女性进行健康体检,有关项目包括常规妇科检查、组织渗液、肿瘤细胞原血红素a/b/c检测,阳性病例再进行TCT检查及病理学检查。结果以病理学检查作为诊断标准,检出宫颈癌10例,检出率为0.05%。另外,以TCT检查作为诊断标准,检出宫颈上皮内瘤样病变1859例(其中CIN III 151例、CIN II 432例、CIN I 1276例),检出率为9.32%。结论肿瘤细胞原血红素a/b/c检测是宫颈癌筛查的适宜技术,在健康体检人群中开展宫颈癌筛查具有明显的实用价值。

Objective To analyze the cervical effusion tumor cell heme a/b/c detection screening results at the time of healthy physical examination and verify the effectiveness of the detection method. Methods 19970 cases of females were given the healthy physical examination, and the related projects included the routine gynecologial examination, tissue effusion and tumor cell heme a/b/c detection, and the positive cases were examined by TCT and pathobiology. Results 10 cases with cervical cancer were detected by the pathobiology examination and the detection rate was 0.05%, besides, 1859 cases of cervical intraepithelial neoplasia including 151 cases of CIN III, 432 cases of CIN II and 1276 cases of CIN I were detected by the TCT and the detection rate was 9.32%. Conclusion The tumor cell heme a/b/c detection is a proper technique of cervical cancer screening, which is of obvious practical value in the healthy population with physical examination.