加味丹参饮治疗老年麻醉患者急性心肌缺血35例

Thirty-Five Cases with Acute Myocardial Ischemia of Senile Patients During Anesthesia Treated with Supplemented Salvia Beverage

目的:观察加味丹参饮治疗老年麻醉患者急性心肌缺血的临床疗效。方法:选取2010年5月—2013年5月就诊于本院的70例老年麻醉术中出现急性心肌缺血患者为研究对象,随机分为对照组和观察组,每组各35例。对照组给予丹香注射液静脉滴注,观察组给予加味丹参饮口服,观察两组患者治疗前后急性心肌缺血相关指标变化情况。结果:对照组有效率为77.14%,观察组有效率为94.28%,两组有效率比较,差异有统计学意义(P<0.05)。两组治疗前在心率、左心室舒张末期压、内皮素(Endothelin,ET)、血清肌酸磷酸激酶(Serum creatine phosphokinase CK)、血清乳酸脱氢酶(Serum creatine phosphokinase,LDH)、血清超氧化物歧化酶(Serum superoxide dismutase,SOD)、丙二醛(malondialdehyde,MDA)比较,差异无统计学意义(P>0.05),两组患者治疗30 min后和治疗末及治疗前比较,差异有统计学意义(P<0.05)。结论:加味丹参饮能保护老年麻醉患者急性心肌缺血,提高麻醉安全性。

Objective：To observe the elinieal effects of Supplemented Salvia Beverage on acute myocardial ischemia of senile patients during anesthesia. Methods ：Totally 70 senile patients with attack of during anesthesia acute myocardial ischemia treated between May,2010 and May,2013 were selected as objects of study and randomly divided into cuntrol group and observation group, with 35 cases in each group. Control group were given intravenous dripping of Danxiang injection while observation group were orally given Supplemented Salvia Beverage. The changes of relevant indicators of myocardial ischemia belore and after treatment in both groups were observed. Results ：The effective rate was 77.14% in control group and 94.28% in observation group;the differeuce had statistical significance（P 〈 0. 05 ）. Before treatment,the difference between the two groups in the levels of heart rate,diastatic pressure of the left ventricle, ET, CK, LDH, SOD and MDA had no statistical significance, but e treatment,the difference between thirty minutes after treatment or at the end of the treatment and before treatment had statistical signifieanee （ P 〈 0.05 ）. Conclusion：Supplemented Salvia Beverage can protect the acute myocardial isehemia of senile patients during anesthesia and en- hance the sat^ty of anesthesia.