护理干预对消化道肿瘤患者生存率和生活质量的影响

Impact of nursing intervention on survival rate and quality of life in patients with gastrointestinal cancer

目的探讨护理干预联合生物治疗对消化道肿瘤患者生存率和生活质量的影响。方法选取2011年3月至2012年9月间哈尔滨医科大学附属肿瘤医院收治的79例消化道恶性肿瘤术后联合生物治疗的患者,按照随机数字表法随机分为观察组（40例）和对照组（39例）。观察组患者予以护理干预,对照组患者行常规护理。比较两组患者1年、2年和3年的生存率,采用症状自评量表（SCL-90）对患者的精神卫生症状进行评价,采用胃肠生活质量量表对患者的生活质量进行评价。结果随访时间为1.5-3.2年,平均随访（2.6±0.7）年。观察组患者1年生存率与对照组比较差异无统计学意义（P〉0.05）,2年和3年生存率均高于对照组,差异均有统计学意义（P〈0.05）。观察组患者各项症状评分均低于对照组,差异有统计学意义（P〈0.05）。观察组患者各项生活质量评分高于对照组,差异有统计学意义（P〈0.05）。结论护理干预联合生物治疗可明显提高患者的生存率,改善患者的生活质量,值得临床推广应用。

Objective To explore the impact of nursing intervention combined with biological treatment on survival rate and quality of life in patients with gastrointestinal cancer. Methods In the study,79 patients with gastrointestinal cancer treated with surgery combined with biological threapy in Cancer Hospital Affiliated to Harbin Medical University from March 2011 to September 2012 were enrolled and randomly assigned to an observation group（ 40 cases） and a control group（ 39 cases）. Patients in the observation group received nursing intervention and patients in the control group received routine nursing. One year,2-year and 3-year survival rate were compared between the two groups. Mental health symptoms were evaluated by the symptom checklist（ SCL-90）,and qualify of life was evaluated by the gastrointestinal qualify of life index. Results Patients were followed up for 1. 5 - 3. 2（ mean 2. 6 ± 0. 7） years. There was no significant difference in 1-year survival rate between two groups（ P〉 0. 05）. The 2-year and 3-year survival rate in the observation group were higher than those in the control group（ P〈 0. 05）. Score of each item on the measure of symptom in the observation group was lower than that in the control group（ P〈 0. 05）. Score of each item on the measure of quality of life in the observation group was lower than that in the control group（ P 0. 05）. Conclusion Nursing intervention combined with biological treatment in the treatment of patients with gastrointestinal cancer can significantly improve the survival rate,promote the quality of life. It is worthy of clinical promotion.