摘要
目的:比较电视胸腔镜与传统开胸肺叶切除术治疗肺癌的临床疗效。方法选择77例肺癌患者作为研究对象,按患者意愿分为电视胸腔镜(VATS)肺叶切除术组43例和传统开胸(OT)肺叶切除术组34例,比较两组手术时间、术中出血量、术后胸管留置时间、住院时间及术后并发症发生率差异,术后1 d、术后3 d、术后5 d 进行疼痛 VAS 评分及术前、术后1 d、术后5 d 进行血清 CRP 检测。结果 VATS 组和 OT 组的手术时间、术后胸管留置时间、住院时间、术中出血量、术后并发症发生率分别为(134±52)min 和(167±45)min,(2.50±0.30)d 和(4.68±0.66)d,(4.77±0.54)d 和(7.20±0.68)d,103±26)mL 和(248±43)mL,11.63%和38.24%,差异均有统计学意义(t =3.563、3.725、9.621、3.402和χ^2=7.504,均 P <0.05)。VATS组和 OT 组术后1 d、术后3 d VAS 评分分别为(6.22±0.82)分和(8.13±0.72)分、(4.46±0.48)分和(6.31±0.54)分,差异均有统计学意义(t =3.927、3.742,均 P <0.05);VATS 组和 OT 组术后1 d、术后5 d 血清 CRP 水平分别为(38.32±9.59)μg/L 和(58.43±10.62)μg/L,(17.71±5.42)μg/L 和(36.65±8.25)μg/L,均较术前明显升高,但 VATS 组术后1 d、术后5 d 血清 CRP 水平均明显低于 OT 组,差异均有统计学意义(t =5.541、6.662,均 P <0.05)。结论胸腔镜肺叶切除术是一种创伤小、恢复快、术后疼痛轻的手术方式,降低患者术后急性期反应,可作为肺癌治疗的推荐治疗方式。
Objective To compare the efficacy of video -assisted thoracoscopic surgery and open -thoracot-omy in the treatment of lung cancer.Methods 77 patients with lung cancer were chose as study objects,all the patients were divided into two groups,43 cases of video -assisted thoracoscopic surgery group (VATS)and 34 cases of open -thoracotomy group (OT)The operative time,blood loss,postoperative chest tube indwelling time and hospi-tal stay and postoperative complication rate were compared.The VAS postoperative 1d,3d,5d after operation were calculated,and the serum CRP preoperative and postoperative 1d,postoperative 5d were detected.Results The oper-ative time,postoperative chest tube indwelling time,hospital stay,the blood loss,the complication rate in VATS group and OT group were (134 ±52)min and (167 ±45)min,(2.50 ±0.30)d and (4.68 ±0.66)d,(4.77 ±0.54)d and (7.20 ±0.68)d,103 ±26)mL and (248 ±43)mL,11.63% and 38.24%,the differences were statistically signifi-cant (t =3.563,3.725,9.621,3.402 and χ^2 =7.504,all P 〈0.05).The VAS postoperative 1d,3d in VATS group and OT group were (6.22 ±0.82)score and (8.13 ±0.72)score,(4.46 ±0.48)score and (6.31 ±0.54)score,the differences were statistically significant,t =3.927,3.742,all P 〈0.05;the serum CRP after 1d,5d postoperative in VATS group and OT group were (38.32 ±9.59)μg/L and (58.43 ±10.62)μg/L,(17.71 ±5.42)μg/L and (36.65 ±8.25)μg/L,which were all higher than those of before surgery,but the serum CRP after 1d,5d postopera-tive in VATS group were lower than those of OT group,the differences were statistically significant(t =5.541,6.662, all P 〈0.05).Conclusion VATS lobectomy is a trauma,quicker recovery,less postoperative pain surgical methods, and can reduce postoperative acute phase reaction,which should be recommended as a treatment for lung cancer.
作者
杨威
Yang Wei(Department of Thoracic Surgery , Beijing Pinggu Hospital , Beijing 101200, China)
出处
《中国基层医药》
CAS
2016年第20期3171-3174,共4页
Chinese Journal of Primary Medicine and Pharmacy
关键词
肺癌
肺叶切除术
胸腔镜
开胸
Lung cancer
Lobectomy
Video -assisted thoracoscopic surgery
Open -thoracotomy