期刊文献+

典型与不典型原发中枢淋巴瘤的MRI及1H-MRS特征研究 被引量:1

下载PDF
导出
摘要 目的 :探讨典型与不典型原发中枢淋巴瘤(primary central nervous system lymphoma,PCNSL)的MRI及1H-MRS特征。方法:回顾性分析48例经病理证实的PCNSL常规MRI及1H-MRS资料,定性分析典型与不典型PCNSL的常规MRI特征,定量分析胆碱(Cho)/肌酸(Cr)、Cho/N-乙酰天门冬氨酸(NAA)值及脂质-乳酸峰(lip-lac)等级,并将两者进行对比。结果:典型PCNSL 27例,呈等或稍低信号,增强后呈显著均匀结节样强化;不典型PCNSL 21例,信号混杂,出现坏死(9例)、出血(6例),增强后7例呈环形强化,11例呈斑片样强化,2例呈线样强化,1例无强化。典型与不典型PCNSL的1H-MRS均可见Cho峰升高、NAA峰降低、不同等级的lip-lac峰。但典型PCNSL的Cho/Cr值较不典型PCNSL高(P=0.02);高耸的5级lip-lac峰是PCNSL的特征性表现。结论:典型与不典型PCNSL的MRI及1H-MRS有一定特征,两者结合对PCNSL的诊断具有重要价值。
出处 《南京医科大学学报(自然科学版)》 CAS CSCD 北大核心 2016年第10期1229-1232,共4页 Journal of Nanjing Medical University(Natural Sciences)
  • 相关文献

参考文献12

  • 1Kuker W, Nagele T, Korfel A,et al. Primary central ner-vous system lymphomas (PCNSL):MRI features at pre- sentation in 100 patients[J]. J Neurooncol,2005,72(2): 169-177.
  • 2Erdag N, Bhorade RM, Alberico RA, et al. Primary lym- phoma of the central nervous system:typical and atypical CT and MR imaging appearances [J]. AJR Am J Roentgenol, 2001,176(5) : 1319-1326.
  • 3Haldorsen IS, Krhkenes J, Krossnes BK,et al. CT and MR imaging features of primary central nervous system lym- phoma in Norway, 1989-2003[J]. AJNR Am J Neuroradi- ol, 2009,30 (4) : 744-751.
  • 4Haldorsen IS,Espeland A,Larsson EM. Central nervous system lymphoma:characteristic findings on traditional and advanced imaging [J]. AJNR Am J Neuroradiol, 2011,32(6) :984-992.
  • 5Tang YZ, Booth TC, Bhogal P, et al. Imaging of primary central nervous system lymphoma [J ]. Clin Radiol, 2011, 66(8) : 768-777.
  • 6Lee HY,Kim HS,Park JW,et al. Atypical imaging fea- tures of Epstein-Barr virus-positive primary central ner- vous system lymphomas in patients without AIDS[J]. A- JNR Am J Neuroradiol, 2013,34 (8) : 1562-1567.
  • 7Ichikawa Y, Maeda M, Ishida M,et al. Unusual MRI find- ings in primary central nervous system lymphoma pre- senting diffuse linear enhancements located in the perivascular space [J]. J Neurol,2006,253 (8): 1094- 1096.
  • 8Sugie M,Ishihara K,Kato H,et ah Primary central ner- vous system lymphoma initially mimicking lymphomatosis cerebri:an autopsy case report [J]. Neuropathology,2009, 29(6) :704-707.
  • 9Raizer JJ,Koutcher JA,Abrey LE,et ah Proton magnetic resonance spectroscopy in immunocompetent patients with primary central nervous system lymphoma[J]. J Neuroon- col, 2005,71 (2):173-180.
  • 10Lu SS,Kim SJ,Kim HS,et ah Utility of proton Mr spec- troscopy for differentiating typical and atypical primary central nervous system lymphomas from tumefactive de- myelinating lesions[J]. AJNR Am J Neuroradiol, 2014,35 (2) :270-277.

二级参考文献31

  • 1张皓,沈天真,陈星荣,缪竞陶.DSC MR灌注成像在胶质瘤术前分级中的价值初探[J].中国医学影像技术,2004,20(8):1193-1196. 被引量:11
  • 2温洋,戴建平,高培毅,李少武,孙学进.ASL在胶质瘤分级中的初步应用[J].中国医学影像技术,2005,21(9):1371-1375. 被引量:17
  • 3那婧,谢德轩,刘鹏飞,周洋.脑胶质瘤MR灌注成像和病理分级对照研究[J].中国临床医学影像杂志,2006,17(3):121-123. 被引量:6
  • 4温洋,戴建平,高培毅,艾林,陈红燕.MR动脉质子自旋标记与动态磁敏感对比增强灌注技术在脑胶质瘤分级中的价值[J].中华放射学杂志,2007,41(4):363-365. 被引量:12
  • 5Detre JA, Leigh JS, Williams DS, et al. Perfusion Imaging [ J ]. Magn Reson Med, 1992,23 ( 1 ) : 37-45.
  • 6Roberts DA, Detre JA,Bolinger L,et al. Qualitative mag- netic resonance imaging of human brain perfusion at 1.5T using steady-state inversion of arterial water [J]. Proc Natl Acad Sci, 1994,91 ( 1 ) : 33-37.
  • 7Barbier EL,Lamalle L, Decorps M,et al. Methodology of brain perfusion imaging [J]. J Magn Reson Imaging, 2001,13(4) :496-520.
  • 8Luh WM,Wong EC,Bandettini PA,et al. QUIPSS Ⅱ with thin-slice TI1 periodic saturation:a method for improving accuracy of quantitative perfusion imaging using pulsed arterial spin labeling[J]. Magn Reson Med, 1999,41 (6): 1246-1254.
  • 9Yongbi MN,Fera F,Yang Y,et al. Pulsed arterial spin la-beling:comparison of multisection baseline and functional MR imaging perfusion signal at 1.5 and 3.0 T:initial re- suits in six subjects[J]. Radiology,2002,222 (2):569- 575.
  • 10Wolf RL, Wang J J, Wang SM, et al. Grading of CNS neo- plasms using continuous arterial spin labeled perfusion MR imaging at 3 tesla [J]. J Magn Reson Imaging, 2005,22(4) : 475-482.

共引文献16

同被引文献10

引证文献1

二级引证文献1

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部