“治未病”思想防治化疗后骨髓抑制探讨

Discussion on Prevention and Treatment of Bone Marrow Depression after Chemotherapy in " Prevention of Disease"

化疗是恶性肿瘤综合治疗的重要手段之一,化疗后引起骨髓抑制是临床常见毒副反应,患者常因此被迫延迟化疗,或减少剂量甚至终止化疗,影响化疗如期进行及临床疗效,从而使患者的生活质量明显下降。骨髓抑制作为恶性肿瘤整体治疗中出现的一类变证,其中医病机以脾肾亏虚为主,化疗作为"药邪之毒"侵犯已虚之机体,造成了脏腑精气进一步亏损。基于肿瘤病变的基础存在,将"治未病"思想贯穿于肿瘤化疗的全过程,对防治化疗引起的骨髓抑制、促进患者康复及改善生存质量具有重要的临床指导意义。

Chemotherapy is an important means of comprehensive treatment of malignant tumors, bone marrow suppression caused by chemotherapy is a common clinical toxicity of chemotherapy patients often forced to delay or reduce the dose, or even termination of chemotherapy, the impact of chemotherapy on schedule and clinical efficacy, leaving the quality of life of patients significantly de- creased. Bone marrow suppression as the overall treatment of malignant tumors that appear in a class of variable syndrome that TCM spleen and kidney deficiency, chemotherapy as ＂medicine evil poison＂ has violated the virtual body, causing further wasting organs essence . Based on the basis of the presence of tumor lesions, the ＂prevention of disease＂ Thought throughout the entire process of cancer chemotherapy, prevention and treatment of chemotherapy--induced bone marrow suppression, and promote the rehabilitation of patients and improve the quality of clinical significance.