成人呼吸道病原九项临床应用初探

A Preliminary Study on Clinical Application of Nine Adult Respiratory Pathogens

目的:探讨呼吸道抗体九项联检在成人呼吸道感染诊治中的应用价值。方法:对2015年2月-2016年2月446例以肺炎、支气管炎、哮喘急性发作和慢阻肺急性加重为主的成人呼吸道感染患者的血清行呼吸道抗体九项检查。结果:总体阳性检出率为25.11%(112/446),其中阳性检出病原体中检出率最高的为支原体(41.07%)、其次为军团菌(32.14%)。肺炎患者的综合阳性检出率最高(31.17%)。结论:呼吸道抗体九项联检用于呼吸道感染诊断有一定的价值,但在早期诊断上有局限性。此方法也可用于呼吸道病原学临床流行病调查。

Objective： To discuss the value of nine-item respiratory antibody co-detection in the diagnosis of adult respiratory tract pathogens. Method： Serum samples were collected from 446 adult patients who were hospitalized and diagnosed as pneumonia, bronchitis, acute asthma or acute exacerbation of chronic obstructive pulmonary disease from February 2015 to February 2016.Then the serum samples were tested by nine-item respiratory antibody co-detection.Result： The total positive rate was 25.11%（1121446）, while the most common pathogen was myeoplasma（41.07%）, followed by the legionena（32.14%）.Among these patients, the positive rate of pneumonia was the highest（31.17%）.Conclusion： Nine-item respiratory antibody co-detection has certain application value in the diagnosis of respiratory tract infection, though imitated in early diagnosis.Meanwhile, it can be used for the investigation of clinical epidemiology of respiratory pathogens.