摘要
New [1＋1] and 62-membered [2＋2] Schiff base macrocycles containing a 2,6-diamidopyridine subunit have been synthesized by condensation reaction of the precursors pyridine-2,6-dicarboxamide and 1,10- bis（2＇-formylphenyloxy）decane in the presence of phosphoric acid via a one-pot process. The cyclo- condensed products were effectively isolated by gel column chromatography and characterized by 1H NMR, FTIR, mass spectrometry and X-ray analysis. The two macrocycles have a twisted structure, and not an open ＇circular＇ conformation in the solid state.
New [1＋1] and 62-membered [2＋2] Schiff base macrocycles containing a 2,6-diamidopyridine subunit have been synthesized by condensation reaction of the precursors pyridine-2,6-dicarboxamide and 1,10- bis（2＇-formylphenyloxy）decane in the presence of phosphoric acid via a one-pot process. The cyclo- condensed products were effectively isolated by gel column chromatography and characterized by 1H NMR, FTIR, mass spectrometry and X-ray analysis. The two macrocycles have a twisted structure, and not an open ＇circular＇ conformation in the solid state.
基金
supported by the National Natural Science Foundation of China (No. 21061003)
the ‘Chun-Hui’ Fund of Chinese Ministry of Education (No. Z2012054)
