期刊文献+

DNA疫苗的研究进展 被引量:5

Study on Development of DNA Vaccines
下载PDF
导出
摘要 回顾了DNA疫苗的发展历程,综述了DNA疫苗基础研究和应用研究的新进展,探讨了DNA疫苗的优越性、存在问题及发展前景. The paper looks back on the developing course of DNA vaccines and sums up the progress in the basic and applied studies, the advantage and disadvantage, and prospects of DNA vaccines are also discussed.
作者 周世力
出处 《江汉大学学报(社会科学版)》 2002年第2期80-83,共4页 Journal of Jianghan University(Social Science Edition)
关键词 DNA疫苗 免疫学机制 研究进展 基因疫苗 分子生物学 免疫反应 DNA vaccines immunology mechanism research advances
  • 相关文献

参考文献3

二级参考文献17

  • 1[1]Babiuk LA. Broadening the approaches to developing more effective vaccines. Vaccine. 1999(17): 1587 - 1595.
  • 2[2]Wolff JA, Malone RW, Williams P, Chong W, Acsadi G, Jani A and Felgner PL. Direct Gene Transfer into mouse muscle in vivo.Science. 1999(274): 1465 - 1468.
  • 3[3]Dubensky TW, Driver DA, Polo JM, Bell BA, Latbam EM, IbanezCE, Chada S, Brumm D, Banks TA, Mento SJ, Jolly DJ and Chang SMW. Sindbis virus DNA- based expression vectors: utility for in vitro and in vivo gene transfer. J. Virol. 1996(70): 508 - 519.
  • 4[4]Williams RS, Johnston SA, Riedy M, DeVit MJ, Me Elligott SG and Sanford JC. Introduction of foreign genes into tissues of living mice by DNA - coated microprojectiles. Proc. Natl. Acad. Sci.USA. 1991 (88): 2726 - 2730.
  • 5[5]Krieg AM, Yi A - K, Matson S, Waldschmidt TJ, Bishop GA,Teasdale R, Koretzky GA and Klinman DM. CpG motifs in bacterial DNA trigger direct B - cell activation . Nature. 1995 (374):546 - 549.
  • 6[6]Kent sj, stallard v, corey l, hu s- l, morton wr, gritz l, panicali dl and greenberg pd. Analysis of cytotoxic T- lymphocyte responses to SIV proteins in SIV- infected macaques using antigen- specif-ic stimulation with recombinant vaccinia and fowlpox viruses.AIDS Res. Hum. Retrovirol. 1994(10): 551 - 560.
  • 7[7]Sizemore dr, branstrom aa and sadoff jc. Attenuated Shigella as a DNA delivery vehicle for DNA- mediated immunization. Science.1996(270) :299 - 302.
  • 8[8]Stribling r, brunette E, liggitt D, gaensler k and debs r. Aerosol gene delivery in vivo. Proc. Natl. Acad. Sci. USA. 1992 (89):11277 - 11281.
  • 9[9]Caplen nj, alton ewfw, middleton pg et al. Liposome - mediated CFTR gene transfer to the nasal epithelium of patients with cystic fibrosis. Nature Med. 1995 (1): 39 - 46.
  • 10Donnelly J J,Life Sci,1997年,60卷,163页

共引文献13

同被引文献98

引证文献5

二级引证文献14

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部