摘要
目的采用Meta分析评价心脏外科手术中应用血液回收技术的血液保护效果。方法计算机检索Cochrane图书馆、PubMed、Embase、CINAHL以及中国知网数据库。收集关于心脏外科手术使用自体血回收的随机对照试验，按Cochrane系统评价方法，评价所纳入研究的文献质量，并提取有效数据后采用RevMan5．1软件进行Meta分析。结果纳入11项研究，共计2046例患者。与对照组比较，应用血液回收技术能够减少围手术期红细胞的使用率[比值比（oddaradio，OR）=0．68，95％置信区间（confidence interval，CI）（0．53，0．87）]，减少围手术期新鲜冰冻血浆的使用率[OR=1．53，95％CI（1．02，2.31）]，围手术期血小板的使用率差异无统计学意义[OR=O．86，95％CI（0．56，1．32）]，术后并发症的发生率差异无统计学意义[OR=1．14，95％CI（0．92，1．41）]。结论心脏手术中使用自体血回收技术可以减少红细胞和新鲜冰冻血浆的输注，具有一定的血液保护效果，且不会增加术后并发症的发生率。
Objective Effects of intraoperative autologous blood salvage on bood conservation in patients undergoing cardiac surgery. Methods We electronically searched Cochrane library, PubMed, Embase, CINAHL, CNKI. Randomized controlled trials about autologous blood salvage on blood conservation during cardiac surgery were indentified. Study selection and meta-analysis were conducted according to the Cochrane Handbook for systematic reviews. Date were extracted and analyzed by RevManS.1 software. Results Eleven studies including a total of 2 046 patients were included. The results showed that compared with the control group, the application of blood salvage equipment can reduce the use of red blood cells [odda radio（OR）=0.68, 95% confidence interval（C/） （0.53, 0.87）], and fresh frozen plasma [ 0R=1.53, 95%CI （1.02, 2.31）] in the perioperative period. However, there was no significant difference in the use of platelet [OR=0.86, 95%CI （0.56, 1.32）] and postoperative complications [OR=l.14, 95%CI （0.92, 1.41）] between control and treatment groups. Conclusions The current evidence suggests that the use of blood salvage device during cardiac surgery can reduce the transfusion of fresh frozen plasma and red blood cells, producing blood conservation. The autologous blood salvage does not increase the incidence of postoperative complications.
出处
《国际麻醉学与复苏杂志》
CAS
2016年第10期896-900,908,共6页
International Journal of Anesthesiology and Resuscitation
基金
国家自然科学基金（81060318）
