南昌市HIV/AIDS病人生存质量现状及其影响因素

Quality of life and its associated factors among people living with HIV/AIDS in Nanchang

目的了解南昌市艾滋病病毒(HIV)感染者/艾滋病(AIDS)病人(简称HIV/AIDS病人)生存质量现状,并探讨其影响因素。方法 2015年1-6月,选择南昌市东湖区和青云谱区疾病预防控制中心登记并确诊的HIV/AIDS病人230例,调查生存质量现况。应用MOS-HIV量表评价HIV/AIDS病人生存质量,采用t检验、方差分析和多元线性逐步回归方法分析其生存质量的影响因素。结果获有效问卷225份,HIV/AIDS病人生理健康总分为(51.88±7.04)分,心理健康总分为(49.29±6.60)分。单因素分析显示:不同年龄、婚姻状况、收入情况、就业情况、CD4+T淋巴细胞计数在生理和心理领域得分差异均有统计学意义(P<0.05)。多元线性逐步回归表明:CD4+T淋巴细胞计数、收入、就业情况、婚姻状况、年龄、文化程度是影响HIV/AIDS病人生存质量的主要因素。结论南昌市HIV/AIDS病人生存质量较低,并受多种因素影响,应加强对年老、失业、独居HIV/AIDS病人的关怀与支持。

Objective To understand the quality of life of people living with HIV/AIDS（PLWHA）and explore its impact factors.Method A cross-sectional survey with cluster sampling of 230 PLWHA was conducted in Nanchang,during January to June,2015.MOS-HIV was used to evaluate the quality of life among PLWHA.Studenttest,ANOVA and multiple linear stepwise regression were applied to analyze the risk factors related to quality of life.Results A total of 225 available questionnaires were finished.The physical health summary（PHS）and mental health summary（MHS）scores were 51.88±7.04 and 49.29±6.60,respectively.Univariate analysis showed that the age,marital status,income,employment and CD4＋ cell count were associated with the quality of life（P〈0.05）.Multiple linear regression analysis showed that CD4＋ cell count,income,employment,marital status,age and education were the main factors influencing the quality of life among 225 PLWHA.Conclusion The overall health quality of life were generally poor,which were influenced by a series of factors among 225 PLWHA in Nanchang.It is important to strengthen social support and care for PLWHA,esp.those who are elderly,unemployed or living alone.