顺德地区421例甲真菌病致病菌分离培养分析

Culture analysis of 421 cases of onychomycosis of pathogenic fungi isolated in Shunde area

目的了解近4年顺德地区的甲真菌病病原菌的菌种类型和构成。方法对甲屑真菌直接镜检阳性的421例甲真菌病患者的甲屑标本进行真菌分离培养以及菌种鉴定。结果 421例甲真菌病患者中,真菌分离培养阳性数为278例,阳性率为66.03%,酵母菌属176例占63.31%,其中白色念珠菌、近平滑念珠菌、热带念珠菌分别占25.54%、18.35%、11.87%;皮肤癣菌91例占32.73%,其中红色毛癣菌、须癣毛癣菌分别占30.21%、1.80%;霉菌11例占3.96%。结论临床分型主要以远端甲下型(DLSO)为主,主要致病菌为酵母菌,其次为皮肤癣菌;菌种则以红色毛癣菌、白色念珠菌、近平滑念珠菌、热带念珠菌多见。

Objective To understand the types of bacteria pathogens of onychomycosis in Shunde area during the last 4 years and constitution.Methods on a chip fungal microscopic examination of positive of 421 cases of onychomycosis in patients with a crumb specimens of fungal culture and strain identification. Results 421 cases of onychomycosis, the fungal isolate culture positive number 278 patients, the positive rate was 66.03%, Among them, yeast 176 cases accounted for 63.31%, of which Candida albicans, Candida parapsilosis and Candida tropicalis accounted for 25.54%, 18.35%, 11.87%; dermatophytes 91 cases（32.73%, of which Trichophyton rubrum and Trichophyton accounted for 30.21% and 1.80%; mould in 11 cases accounted for 3.96%. Conclusion clinical classification based mainly on the distal nail type（DLSO）, The main pathogenic fungi were yeasts, Secondly for dermatophytes; Fungi strains in Trichophyton rubrum, Candida albicans, Candida parapsilosis, Candida tropicalis were more isolated.