摘要
目的研究白毛七化学成分。方法采用硅胶柱色谱、Sephadex LH-20葡聚糖凝胶柱色谱、制备液相色谱等色谱技术进行分离纯化,通过理化方法和波谱数据进行分析和结构鉴定。结果从白毛七中分离鉴定了9个化合物,分别为securigranⅠ（1）、4α,8β-dihydroxy-5α（H）-eudesm-7（11）-en-8,12-olide（2）、chloraeudolide（3）、zedoarolide B（4）、serralactone C（5）、peroxiatractylenolideⅢ（6）、spicachlorantin B（7）、shizukaol C（8）、3-（3,4-dihydroxyphenyl）-acrylicacid 1-（3,4-dihydroxyphenyl）-2-methoxycarbonylethyl ester（9）。结论化合物1~9均为首次从该植物中分离得到。
Objective To investigate the chemical compositions from rhizomes of Chloranthus multistachys Pei.. Methods The compounds were isolated by column chromatography with silica gel, Sephadex LH-20and preparative HPLC, and the structures were elucidated by the physical and chemical methods and spectral data. Results Nine compounds were isolated, and their structures were determined as securigran I （1）, 4a, 8fl-dihydroxy-5a （H）-eudesm-7 （11）-en-8, 12-olide （2）, chloraeudolide （3）, zedoarolide B （4）, serralactone C （5）, peroxiatractylenolide Ⅱ （6）, spicachlorantin B （7）, shizukaol C （8）, and 3-（3, 4-dihydroxyphenyl）-acrylicacid 1-（3, 4-dihydroxyphenyl）-2-methoxycarbonylethyl ester （9）. Conclusion Compound 1 - 9 have been isolated from this plant for the first time.
出处
《中南药学》
CAS
2016年第9期959-962,共4页
Central South Pharmacy
基金
陕西省科技统筹创新工程计划项目(No.2013KTCQ03-14)
关键词
白毛七
化学成分
结构鉴定
Chloranthus multistachys Pei.
chemical composition
structure identification
