戊型肝炎检测研究进展

Research progress in detection of hepatitis E

戊型肝炎是由戊型肝炎病毒(HEV)引起的一种急性病毒性肝炎。虽然它在全球都有发病报告,但主要发病于亚洲和非洲的一些发展国家。我国也是戊型肝炎的高发区。部分地区曾有暴发报告。戊型肝炎的特点与甲型肝炎相似,主要传播途径为粪-口传播。戊型肝炎的暴发也具有一定的季节性,尤其在多雨的地带,最容易暴发。戊型肝炎有较高的病死率,尤其对于孕妇、老年人。近年的研究显示,人们对于戊型肝炎的认识还远远不足,我们必须加强对HEV感染的重视,要做到尽早诊断,尽早治疗,及时隔离传染源,快速控制传播。本文就戊型肝炎的一些诊断方法进行评述。

Hepatitis E virus （HEV） is one of the most common causes of acute viral hepatitis worldwide, especially in developing countries of Asia and Africa. There were high-prevalence of hepatitis E in China and its outbreaks reported in some parts of the country. The clinical characteristic of hepatitis E is similar with one of hepatitis A. Hepatitis E was mainly transmitted by the fecal-oral way. Its outbreak appeared certain seasonally, especially in the rainy area. In acute cases, a higher mortality rate has been reported in patients with hepatitis E, especially pregnant women and the aged. Some investigation has shown that people＇s understanding to hepatitis E was insufficient recently. So we must pay more attention to the HEV infection, including early diagnosis, early treatment, timely isolated and fast transmission control. This paper reviews some new diagnostic methods of HEV.