同型半胱氨酸水平与急性脑梗死关系研究

Study on the correlation of homocysteine levels and acute cerebral infarction

目的研究同型半胱氨酸(Hcy)水平与急性脑梗死的关系,以指导临床预防及治疗。方法选择2012年1月-2013年6月在平煤医疗集团总医院神经内科急性脑梗死患者206例作为观察组,另选择190例本院健康体检者作为对照组,两组均于清晨空腹采集静脉血2ml,在2h内完成测定项目,采用分值环酶法测定血清Hcy水平,并进行对比分析。结果急性脑梗死组患者血浆Hcy水平(18.19±7.26μmol/L)明显高于对照组(11.23±5.46μmol/L),两者差异有统计学意义(P<0.05)。结论急性脑梗死患者血清Hcy水平明显高于正常值。

Objective To study the correlation of homocysteine levels and acute cerebral infarction. Methods The homocysteine （Hey） levels from 206 patients with acute cerebral infarction as obseriation group and 190 healthy subjects as control group were determined in general hospital of medical group pingmeishe ma from Jan of 2012 to Jun of 2013. Results Plasma Hcy level was （18.19±7.26） umol/L in patients with acute cerebral infarction and（11.23±5.46） umol/L in control group. The former was significantly higher than the latter（P〈0.05）. Conclusion High plasma Hey level was common in acute cerebral infarction.