公民逝世后器官捐献供肾移植临床分析

Clinical analysis on kidney transplantation from donation after citizen death

目的探讨公民逝世后器官捐献供肾移植的近期临床效果。方法公民逝世后器官捐献供肾移植73例，供者43例，其中本院器官获取组织42例，外院器官获取组织分享1例。分析肾移植术后人/肾存活率和并发症的发生情况。结果73例受者随访9～38个月，术后6个月、1年的人/肾存活率分别为97.3％/94.5％、94.5％/91.8％。10例（13.7％）受者发生移植肾功能恢复延迟，15例（20.5％）受者术后发生急性排斥反应，21例（28.8％）受者发生肺部感染。2例受者移植肾丢失，4例受者移植肾带功死亡。结论公民逝世后器官捐献供肾移植近期疗效较好，是解决供肾来源的有效途径。

Objective To investigate the clinical effect of kidney transplantation from donation after citizen death. Method From February 2013 to April 2013,the clinical data of 73 cases of kidney transplantation from donation after citizen death were retrospectively reviewed. Patient/ kidney survival rate and complications were analyzed. Results There were 43 deceased donors,including 42 cases from our hospital and 1 case from a cooperative hospital. The recipients（73 cases）were followed up for 9 to 38 months. The 6-month and 1-year patient/ graft survival rates were 97. 3% / 94. 5% and 94. 5% / 91. 8% . Delay graft function（DGF）occurred in 10 recipients（13. 7% ）,acute rejection occurred in 15 recipients （20. 5% ）,and pneumonia developed in 21 cases（28. 8% ）. There were 2 cases of additional nephrecto-mies and 4 recipients died with a functional graft. Conclusion The kidney transplantation from donation after citizen death is safe and feasible in short-term. It represents a potential method to expand the donor pool.