胰腺实性假乳头状瘤45例手术治疗分析

Surgical treatment and prognosis analysis of solid pseudo papillary tumor of the pancreas:a report of 45 cases

目的总结胰腺实性假乳头状瘤的外科治疗体会。方法45例胰腺实性假乳头状瘤患者，均行手术治疗，其中11例行胰腺局部切除术，20例行胰体尾切除术，5例行胰体尾联合脾脏切除术，9例行胰十二指肠切除术。结果8例发生消化不良，2例患者术后发生胰瘘，胸腔积液2例，切口液化、感染2例，早期（术后24 h 内）消化道出血1例。所有患者均保守治疗均痊愈出院。43例获得随访，随访时间6～160个月，平均（41.5±1.5）个月，术后均无转移、复发及死亡。结论腺假乳头状瘤为潜在低度恶性肿瘤，好发于年轻女性，手术是唯一根治的治疗方式，预后一般较好。

Objective To discuss the surgical treatment and prognosis of solid pseudo papillary tumor of the pancreas. Methods The clinical data of 45 patients with solid pseudo papillary tumor of the pancreas were analyzed retrospectively. Surgical treatment was performed in all cases,including 11 cases of local excision of the pancreas,20 cases of resection of the pancreatic body and tail,5 cases of resection of the pancreatic body,tail plus spleen,and 9 cases of pancreaticoduodenectomy. Results A total of 43 ca-ses were followed up for 6 ~ 160 months,with an average of（41. 5 ± 1. 5）months. There were 8 cases of dyspepsia,2 cases of pancreatic fistula,2 cases of pleural effusion,2 cases of incision liquefaction and in-fection,and 1 case of early hemorrhage of the digestive tract. All patients were cured by conservative treat-ment. No metastasis,recurrence or death occurred after the operation. Conclusion The pseudo papillary tumor of the pancreas is a potential low grade malignant tumor which mainly appears in females. Surgery is the only radical treatment and its prognosis is generally good.