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Crystal Structures of Arabidopsis thaliana Oxalyl- CoA Synthetase Essential for Oxalate Degradation

Crystal Structures of Arabidopsis thaliana Oxalyl- CoA Synthetase Essential for Oxalate Degradation
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摘要 Dear Editor Oxalic acid, the simplest of all dicarboxylic acids, is widely found in all plant species (FranceschJ and Nakata, 2005). Two pathways exist for oxalate degradation in plants: degradation via oxalate oxidase and ATP- and CoA-dependent decarboxylation of oxalate through a poorly studied series of enzymatic reactions (Giovanelli and Tobin, 1961). OxalyI-CoA synthetase, the enzyme that initiates the second degradation pathway was recently identified in Arabidopsis thaliana as a protein encoded by ACYL-ACTIVATING ENZYME3 (AAE3). It was shown that AAE3- dependent degradation of oxalate is important for normal seed development and for defense against oxalate-producing fungal pathogens in Arabidopsis (Foster et al., 2012). In addition, it was shown recently that AAE3 also plays a role in seed development in maize and rice (Wang et al., 2011). Dear Editor Oxalic acid, the simplest of all dicarboxylic acids, is widely found in all plant species (FranceschJ and Nakata, 2005). Two pathways exist for oxalate degradation in plants: degradation via oxalate oxidase and ATP- and CoA-dependent decarboxylation of oxalate through a poorly studied series of enzymatic reactions (Giovanelli and Tobin, 1961). OxalyI-CoA synthetase, the enzyme that initiates the second degradation pathway was recently identified in Arabidopsis thaliana as a protein encoded by ACYL-ACTIVATING ENZYME3 (AAE3). It was shown that AAE3- dependent degradation of oxalate is important for normal seed development and for defense against oxalate-producing fungal pathogens in Arabidopsis (Foster et al., 2012). In addition, it was shown recently that AAE3 also plays a role in seed development in maize and rice (Wang et al., 2011).
出处 《Molecular Plant》 SCIE CAS CSCD 2016年第9期1349-1352,共4页 分子植物(英文版)
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