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右美托咪定在宫颈癌根治术硬膜外麻醉中的镇静效果评价 被引量:2

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摘要 目的:探讨右美托咪定在宫颈癌根治术硬膜外麻醉中的镇静效果。方法:按照入院顺序将96例择期行硬膜外麻醉下宫颈癌根治术的患者随机分为实验组和对照组,每组48例,对照组给予常规硬膜外麻醉,实验组在此基础上给予右美托咪定镇静,观察两组患者不同时间点的Ramsay镇静评分、脑电双频指数(BIS)、心率、血压及术后不良反应发生率。结果:实验组手术开始15min、手术开始30 min、术毕BIS、心率和血压均明显低于对照组,差异有统计学意义,P<0.05;实验组术后注射痛、呼吸抑制以及低血压发生率明显低于对照组,差异有统计学意义,P<0.05。结论:右美托咪定对硬膜外麻醉下宫颈癌根治术中的Ramsay镇静评分、BIS、心率、血压的影响积极,有明显的镇静效果。
作者 聂德魁
出处 《实用中西医结合临床》 2016年第8期61-62,共2页 Practical Clinical Journal of Integrated Traditional Chinese and Western Medicine
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  • 1耿毅.宫颈癌手术百年发展历程[J].肿瘤学杂志,2004,10(5):289-292. 被引量:14
  • 2耿志宇,许幸.瑞芬太尼的临床药理学[J].国外医学(麻醉学与复苏分册),2004,25(4):203-206. 被引量:208
  • 3Afonso J,P.eis F.Dexmedetomidine: current role in anesthesia and intensive care[J]. F{ev Bras Anestesiol, 2012,62(1 ): 118-133.
  • 4Farag E,Argalious M,Abd-EIsayed A,et al.The Use of Dexmedetomidine in Anesthesia and Intensive Care:A Peview[J]. Curr Pharm Des, 2012,18(38):6257-6265.
  • 5Kolaric N,Macan JS,Majeric-Kogler V,et al.Anesthesia and perioperative management of patients with resection for esophageal carcinoma[J]. Lijec Vjesn, 2005; 127(11-12): 293-298.
  • 6Busti AJ,Hooper JS,Amaya CJ,et al. Effects of perioperative antiinflammatory and immunomodulatin6 therapy on surgical wound healing[J]. Pharmacotherapy, 2005,25(1 ].): 1566-1591.
  • 7Miki O,Kusunoki M,Inoue Y,et al. Pemodeling of the immunoinflammatory network system in elderly cancer patients: impIications of inflamm-agin6 and tumor-specific hyperinflammation[J].Surg Today, 2008,38(10): 873-878.
  • 8Moura E,Afonso J,Hein L,et aI.Alpha2-adrenoceptor subtypes involved in the regulation of eatecholamine release from the adrenal medulla of mice[J]. Br J Pharmacol, 2006, 149(8): 1049-1058.
  • 9Yeh YC,Sun WZ,Ko WJ,et al. Dexmedetomidine prevents alterations of intestinal microcirculation that are induced by surgical stress and pain in a novel rat model[J].Anesth Analg,2012,115(1):46-55.
  • 10Bekker A,Haile M,Kline E,et aI.The Effect of Intraoperative infusion of Oexmedetomidine on the Quality of Recovery After Major Spinal Surgery[J]. J Neuresurg Anesthesiol, 2013,25 ( 1 ): 16-24.

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