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帕金森病异动症研究进展 被引量:1

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摘要 帕金森病(Parkinson’s disease)是一种常见于中老年的神经系统退行性疾病,主要以黑质多巴胺能神经元进行性退变和路易小体形成的病理变化,纹状体区多巴胺递质降低、多巴胺与乙酰胆碱递质失平衡的生化改变,临床上以静止性震颤、运动迟缓、肌强直等运动症状和嗅觉减退、便秘、睡眠行为异常和抑郁等非运动症状为显著特征。我国65岁以上人群总体患病率为1700/10万,并随年龄增长而升高,
出处 《中华医学杂志》 CAS CSCD 北大核心 2016年第41期3350-3352,共3页 National Medical Journal of China
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