地佐辛对臂丛神经阻滞镇痛效果的影响

Influence by dezocine on analgesic effect by brachial plexus nerve block

目的研究地佐辛复合利多卡因和左布比卡因用于臂丛神经阻滞的镇痛效果。方法 80例美国麻醉医师协会（ASA）Ⅰ-Ⅱ级上肢手术患者,随机分成A、B两组,各40例。A组采用5 mg地佐辛＋1%利多卡因＋0.25%左布比卡因30 ml麻醉,B组采用1%利多卡因＋0.25%左布比卡因30 ml麻醉。记录麻醉起效时间、麻醉维持时间、麻醉不良反应,并比较。结果 A组麻醉维持时间（16.46±3.24）h明显长于B组（8.62±2.48）h（P〈0.05）;两组麻醉起效时间、不良反应发生情况比较差异均无统计学意义（P〉0.05）。结论地佐辛复合利多卡因和左布比卡因用于臂丛神经阻滞能延长麻醉维持时间,临床上值得应用。

Objective To research analgesic effect by dezocine combined with lidocaine and levobupivacaine applied in brachial plexus nerve block.Methods A total of 80 patients with American Society of Anesthesiologists（ASA） Ⅰ~Ⅱ grade upper limb surgery were randomly divided into group A and group B,with 40 cases in each group.Group A received 30 ml of 5 mg dezocine ＋ 1% lidocaine ＋ 0.25% levobupivacaine for anesthesia,and group B received 30 ml of 1% lidocaine ＋ 0.25% levobupivacaine for anesthesia.Anesthesia onset time,anesthesia maintenance time and adverse reactions were recorded for comparison.Results Group A had obviously longer anesthesia maintenance time as（16.46±3.24） h than（8.62±2.48） h in group B（P〈0.05）.There was no statistically significant difference of anesthesia onset time and adverse reactions between the two groups（P〉0.05）.Conclusion Combination of dezocine,lidocaine and levobupivacaine can prolong anesthesia maintenance time in brachial plexus nerve block,and it is worth clinical application.