3583例早产儿视网膜病变的筛查临床分析

Prevalence of retinopathy of prematurity in 3583 cases of preterm infants

目的探讨早产儿视网膜病发病特点及筛查策略。方法使用间接眼底镜及RET-CAM-3对3583例早产儿进行眼底筛查,观察视网膜血管情况。结果 ROP发病率为12.26%,ROP组与非ROP组在胎龄、体重、是否使用呼吸机和吸氧情况方面差异均有显著性(P均<0.05)。结论早产儿视网膜病发病率高,对于出生胎龄小,低出生体重,使用呼吸机及氧气治疗的早产儿及早进行ROP的筛查,首次筛查应在矫正胎龄32周甚至更早进行,早期发现,早期治疗,视力预后往往比较好。

Objective：To analyse the incidence and risk factors of retinopathy of prem aturity（ROP）in xiamen region. Methods：The fundus of 3583 prem ature infants who were examined in Ophthalmology clinic and NICU from february. 2008 to september. 2014. Results：In all the 3583 prem ature infant cases,ROP was found in 439 cases,accounted for 12.26%,Initial examinations with the binocular indirect ophthalmoscopy and the scleral depression and RET-CAM-3 machine began at 4~6 weeks after birth or at 32 weeks postconception. All infants were followed-up until a stable retinal situation was reached. Main Outcome Measures The prevalence of ROP. Conclusions：Earlier screening for ROP is very important. Low birth weight and young gestational age are the most important risk factors in the development of ROP.