SWI在新生儿缺氧缺血性脑病颅内出血中的诊断价值

Diagnostic Value of SWI in HIE with Intracranial Hemorrhages

目的探讨磁敏感加权成像(SWI)在新生儿缺氧缺血性脑病(HIE)颅内出血中的诊断价值。方法对76例临床确诊为缺氧缺血性脑病的新生儿进行1.5T MR检查,常规行T1WI、T2WI、液体衰减反转恢复(FLAIR)扫描,及磁敏感加权成像(SWI)扫描,对比分析研究SWI序列与常规序列在颅内出血灶的检出率及显示情况。结果 76例患儿中,SWI序列共检出46例颅内出血,常规序列(T1WI、T2WI、FLAIR)共检出25例,且均被SWI序列所检出;SWI序列共发现117个出血灶,T1WI发现60个、T2WI 40个、FLAIR 77个,SWI序列对出血灶的检出率明显高于常规序列,差异具有统计学意义(P<0.05),SWI序列在出血灶大小、范围及边界清晰度显示方面均明显优于常规序列。结论 SWI序列在HIE患儿出血灶的检出及显示情况均明显高于常规序列,具有明显优势,为临床诊疗提供了有力的影像学参考依据,可以作为HIE检查的常规序列。

Objective To discuss the diagnostic value of SWI in HIE with intracranial hemorrhages. Methods 1.5T Magnetic Resonance（MR） examination was performed in 76 neonates clinically diagnosed as HIE,the T1WI、T2WI、FLAIR were scan conventionally, as well as SWI scan, the detection rate, display of SWI sequence and conventional sequence in intracranial hemorrhage were compared and analyzed. Results Of the 76 patients, a total of 46 cases of intracranial hemorrhage were detected by SWI sequence,25 cases of intracranial hemorrhage were detected by conventional sequence（T1WI, T2 WI, FLAIR）, which were all detected by SWI sequence; SWI sequence found 117 bleeding foci, T1 WI found 60, T2 WI found 40, FLAIR found 77,the detection rate of SWI sequence on bleeding foci was obviously higher than that of the conventional sequence, the difference had statistical significance（P〈0.05）, the size,range and boundary definition display of SWI sequence in bleeding foci were remarkably superior to than that of the conventional sequence.Conclusion The detection rate and display of SWI sequence in HIE with bleeding foci in neonates are both remarkably higher than that of the conventional sequence, it has evident advantage, and provide a powerful image reference for clinical diagnosis and therapy, which can be used as a routine sequence of HIE tests.