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前列腺特异抗原及相关指标在前列腺癌诊断中的意义 被引量:5

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摘要 目的提高前列腺特异抗原(PSA)在鉴别良性前列腺增生和前列腺癌(Pca)诊断中的应用价值。方法检测84例前列腺增生患者(BPH)和60例Pca患者血清中检测游离PSA(f PSA)和总PSA(t PSA)水平。计算F/T(f PSA/t PSA),检测超声测量前列腺三维直径,计算前列腺体积(PV),得出单位体积PSA浓度(PSAD),两组数据进行统计学分析,根据统计结果计算PSA相关指标的特异性和敏感性。结果两组数据间的F/T、PSAD和PSA年增长率(PSAV)差异均有统计学意义。f PSA/t PSA的特异性达91.2%,敏感性为88.3%;PSAD的特异性达81%,敏感性为52%;PSAV的特异性可达90%、敏感性63%。结论前列腺癌中t PSA、PSAD、PSAV等指标与在前列腺良性增生中的相应指标有明显差异,其敏感性和特异性很高,可以作为前列腺癌诊断的参考依据。
出处 《中国老年学杂志》 CAS CSCD 北大核心 2016年第21期5357-5358,共2页 Chinese Journal of Gerontology
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