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新辅助化疗对宫颈鳞癌Bub1、p53的影响 被引量:2

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摘要 目的:探究新辅助化疗对宫颈鳞癌中Bub1、p53的影响及其机理。方法:在我院接受治疗的宫颈鳞癌患者40例均采用新辅助化疗治疗。根据组织摄取部位不同分为癌旁组和癌中组。观察治疗前后癌旁组和癌中组的Bub1、p53的含量。结果:癌中组的Bub1均增高,p53均降低,接近癌旁组。结论:新辅助化疗治疗宫颈鳞癌临床疗效显著,其机理可能是通过升高Bub1、降低p53含量进行调节,对肿瘤细胞的生长起到了抑制的作用。
出处 《实用中西医结合临床》 2016年第6期32-33,共2页 Practical Clinical Journal of Integrated Traditional Chinese and Western Medicine
基金 甘肃省社会发展类课题(编号:2015CGKJ63)
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