呼吸道合胞病毒感染与支气管哮喘发病机制研究进展

Advancement in the pathogenesis of respiratory syncytial virus infection and bronchial asthma

呼吸道合胞病毒（RSV）是婴幼儿下呼吸道感染最常见的病原体之一，可导致反复喘息和哮喘，被认为在哮喘的发作和加重过程中起重要作用。其相关机制十分复杂，与多种因素相关，包括RSV本身结构及感染后引起的机体细胞和相关因子的改变、信号通路的激活等。

Respiratory syncytial virus （RSV）is one of the most common pathogens caused lower respiratory tract infection in infants, resulting in recurrent wheezing and asthma. RSV plays an important role in asthma attack and exacerbation. The mechanism of wheezing and asthma induced by RSV infection is complicated. It is a result by multiple factors interacted,including： the structure of RSV itself and the changes of the body cells and related factors, signal pathways, eet.