近红外量子点的研究进展

Research Progress in Near-Infrared Quantum Dots

量子点具有优异的光学性能及丰富的表面化学性质,在生物医学分析领域具有较好应用前景。近红外窗口生物成像所具有的背景干扰小、穿透深度大等特点,使得近红外量子点在生物成像应用中更具优势。本文介绍了近红外量子点从早期含Cd、含Pb量子点到近年来新型无Cd、无Pb量子点的发展历程,以及其在生物医学成像领域的应用,着重介绍了新型低毒性近红外量子点的研究进展。

Quantum dots （QDs） have great potential in the application of biomedical detection and metrology due to their excellent optical properties and flexible surface chemistry. Near-infrared （NIR） fluorescent QDs exhibit special superiority for the application of bioimaging because of the low background interference and large penetration depth in the NIR imaging. This article reviewed the synthesis and biomedical imaging applications of the Cd, Pbcontaining and Cd, Pb-free NIR QDs, emphatically introduced the development of the novel low toxic NIR QDs.