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重症手足口病儿童脑脊液中淋巴细胞亚群的变化 被引量：2

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摘要 目的探讨重症手足口病儿童脑脊液(CSF)中淋巴细胞亚群的变化规律。方法运用流式细胞术检测30例重症手足口病儿童(重症手足口病组)和30例对照组儿童CSF中淋巴细胞亚群(CD3+、CD3+CD4+、CD3+CD8+、CD19+、CD16+或CD56+)的绝对值。结果重症手足口病组CSF中CD3+、CD3+CD4+、CD3+CD8+绝对值均高于对照组(P<0.05),CD19+绝对值低于对照组(P<0.05),CD3+CD4+/CD3+CD8+、CD16+或CD56+与对照组比较差异无统计学意义(P>0.05)。结论重症手足口病儿童CSF中细胞免疫发生改变,淋巴细胞亚群的变化在儿童重症手足口病发病机制中可能起重要作用。
作者 胡泽华 林树林 黄玲玲 农凤秋 何康成 李薇
机构地区 广东省东莞市第五人民医院儿科
出处 《广东医学》 CAS 北大核心 2016年第19期2931-2933,共3页 Guangdong Medical Journal
关键词 儿童 手足口病 流式细胞术 淋巴细胞亚群
分类号 R512.62 [医药卫生—内科学]
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参考文献16

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二级参考文献29

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共引文献21

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二级引证文献8

广东医学
2016年 第19期

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