血清前白蛋白(PA)在各类乙型肝炎检测中的临床意义

CLINICAL VALUE OF USING SERUM PREALBUMIN(PA)IN DETECTING VARIOUS TYPES OF HEPATITIS B

目的探究与分析血清前白蛋白(PA)在各类乙型肝炎检测中的临床意义。方法选取临沂市中医医院自2014年3月至2016年3月収治的90例乙型肝炎患者作为观察组,按照疾病类型分组,另选择同时期収治的健康体检人员20例作为对照组,对比几组患者血清PA含量及PA降低患者的百分比。结果急性黄疸型肝炎、慢性肝炎中度、慢性肝炎重度、亚急性重型肝炎、慢性重型肝炎及肝炎后肝硬化患者的血清PA较对照组均出现不同程度的降低,差异具有统计学意义(P<0.05)。急性黄疸型肝炎、慢性肝炎轻度及慢性肝炎中度患者PA降低例数明显低于慢性肝炎重度、亚急性重型肝炎、慢性重型肝炎及肝炎后肝硬化患者,差异具有统计学意义(P<0.05)。结论血清PA水平可作为检测各类乙型肝炎的常见指标,为临床治疗提供参考依据。

Objective To explore and analyze the clinical value of using serum prealbumin （PA） in detec- ting various types of hepatitis B. Methods 90 cases of hepatitis B treated in our hospital formed the observa- tion group from March, 2014 to March, 2016 and further divided into subgroups according to the type of the disease, and other 20 cases of healthy volunteers formed a control group. The serum PA levels and the reduced percentage of serum PA were compared between the groups. Results Compared with the control group, the levels of serum PA in all the observation groups of acute hepatic jaundice, chronic hepatitis, moderate, and severe chronic hepatitis, subacute severe hepatitis and chronic hepatitis were all reduced to various degrees（ P 〈0.05）. The serum PA levels of acute jaundice liver, mild and moderate chronic hepa- titis were significantly lower than those of severe chronic hepatitis, subacute severe hepatitis, chronic hep- atitis and liver cirrhosis （ P 〈0.05 ）. Conclusion Serum levels of PA can be used to detect various types of hepatitis to provide reference for clinical treatment.